摘要
目的:探究婚姻质量对轻度认知功能障碍(MCI)及阿尔茨海默病(AD)患病的影响。方法:运用系统随机抽样法抽取自贡市青杠林社区≥60岁老年居民400人;采用自编的一般情况调查表、婚姻状况表收集入组者人口学等资料;应用简易精神状态检查量表(MMSE)、蒙特利尔认知评估量表(MoCA)对入组者进行认知功能评估;依据《国际疾病分类》第10版(ICD-10)中MCI及AD的诊断标准对有认知功能损害者(MMSE<26分及MoCA<26分)进行诊断;分析婚姻状况对MCI及AD的影响。结果:共345人完成调查,根据目前的婚姻状态分为单身组(47人)及在婚组(298人)。MCI及AD患病率单身组(34.04%,19.15%)明显高于在婚组(20.13%,9.73%)(χ^(2)=6.133,χ^(2)=8.157;P均<0.05)。MCI及AD女性患者中,单身组MMSE及MoCA评分明显低于在婚组(P<0.05或P<0.01);男性患者中,两组间MMSE及MoCA评分差异无统计学意义。二分类Logistic回归分析显示有子女支持、正性解决冲突、共同承担家庭经济负担是MCI与AD患病的保护因素。结论:婚姻是MCI和AD的保护因素,女性较男性更需要婚姻的保护。
Objective:To explore the influence of marriage quality on mild cognitive impairment(MCI)and Alzheimer's disease(AD).Method:A total of 400 elderly residents over 60 years old in Qingganglin community of Zigong City were selected by systematic random sampling method;their demographic data were collected by self-made general situation questionnaire and marital status inventory;cognitive function of the participants was evaluated by mini-mental state examination(MMSE)and the Montreal cognitive assessment(MOCA);and according to the 10 th International Classification of diseases(ICD-10),the cognitive function of the subjects was evaluated by the diagnostic criteria of MCI and AD,patients with cognitive impairment(MMSE<26 and MOCA<26)were diagnosed,and the influence of marital status on MCI and AD was analyzed.Results:A total of 345 people completed the survey and were divided into the single group(n=47)and the married group(n=298)according to the current marital status.The prevalences of MCI and AD in the single group(34.04%,19.15%)were significantly higher than those in the married group(20.13%,9.73%)(χ^(2)=6.133,χ^(2)=8.157;both P<0.05).In MCI and AD female patients,MMSE and MOCA scores in single group were significantly lower than those in married group(P<0.05 or P<0.01);in male patients,there was no significant difference in MMSE and MOCA scores between the two groups.Binary Logistic regression analysis showed that children's support,positive conflict resolution and shared family financial burden were protective factors for MCI and AD.Conclusion:Marriage is a protective factor for MCI and AD.Women need more protection from marriage than men.
作者
蔡本静
蔡端芳
刘波
谭友果
CAI Ben-jing;CAI Duan-fang;LIU Bo;TAN You-guo(Southwest Medical University,Luzhou 646000,China)
出处
《临床精神医学杂志》
CAS
2021年第2期137-139,共3页
Journal of Clinical Psychiatry
