摘要
目的探讨高海拔地区冠状动脉慢血流现象(CSFP)患者生化指标,分析CSFP发生危险因素。方法选择冠状动脉无明显狭窄且存在CSFP的患者98例作为CSFP组(高海拔地区患者48例,低中海拔地区患者50例),同期血流正常的患者101例作为对照组(高海拔地区患者50例,低中海拔地区患者51例)。获取患者入院生化指标并分析CSFP发生高危因素。结果CSFP组ALT、GOT、Na、CK、CG、LDL-C、TG、ET-1高于对照组(P<0.05),HDL-C、NO低于对照组(P<0.05)。高海拔组CG、TG、ET-1高于低中海拔组(P<0.05),NO低于低中海拔组(P<0.05)。ET-1、NO为CSFP发生的独立影响因素(P<0.05)。结论CSFP患者可发生血脂异常,特别是高海拔地区CSFP患者血脂变化更显著,血脂水平的变化是CSFP发生的独立影响因素。
Objective To explore the biochemical indicators of patients with coronary slow flow phenomenon(CSFP)in high altitude areas and to analyze the risk factors of CSFP.Methods A total of 90 CSFP patients with no coronary artery stenosis were selected as the CSFP group(48 patients in high altitude area and 50 patients in low and middle altitude area)and 101 patients with normal blood flow were selected as the control group(50 patients in high altitude area and 51 patients in low and middle altitude area).The biochemical indicators of the patient′s admission were obtained,and the high risk factors of CSFP were analyzed.Results ALT,GOT,Na,CK,CG,LDL-C,TG,and ET-1 in the CSFP group were significantly higher than those in the control group(P<0.05),while HDL-C and NO in the CSFP group were lower than those in the control group(P<0.05).CG,TG and ET-1 in the high altitude group were higher than those in the low and middle altitude group(P<0.05),while NO was lower than that in the low and medium altitude group(P<0.05).ET-1 and NO were independent influencing factors of CSFP(P<0.05).Conclusion Dyslipidemia can occur in patients with CSFP,especially in high altitude areas.The change of blood lipid level is an independent influencing factor of CSFP.
作者
韩晓娟
肖萍
侯海文
HAN Xiaojuan;XIAO Ping;HOU Haiwen(Department of Cardiology,Qinghai Cardiovascular and Cerebrovascular Disease Hospital,Xining 810012,China;ECG Room of Qinghai Cardiovascular and Cerebrovascular Hospital,Xining 810012,China)
出处
《公共卫生与预防医学》
2021年第2期96-99,共4页
Journal of Public Health and Preventive Medicine
关键词
冠状动脉慢血流现象
生化指标
危险因素
Coronary slow flow phenomenon
Biochemical indicators
Risk factors
