摘要
目的探讨胃食管反流病影响因素及中医证型分布情况。方法选择2018年5月至2019年5月胃食管反流病患者100例为观察组,选择同期120例体检健康者为对照组,对观察组患者进行中医辨证分型,分析中医证型的相关因素,对胃食管反流病的影响因素进行单因素和Logistic回归分析,比较两组人员生活质量。结果观察组肝胃郁热证32例,中虚气逆证39例,气郁痰阻证25例,肝热犯胃证3例,瘀血阻络证1例;中虚气逆、气郁痰阻证患者多为女性,中虚气逆证多发于>60岁患者,病程长于肝胃郁热证、气郁痰阻证患者,差异有统计学意义(P<0.05);单因素分析显示,两组在饮酒、高脂饮食、便秘、进食过饱、精神紧张等方面比较,差异有统计学意义(P<0.05),两组在性别、年龄、高盐饮食、咖啡等方面比较,差异无统计学意义(P>0.05);Logistic回归分析显示,饮酒、高脂饮食、便秘、进食过饱和精神紧张是胃食管反流病的独立危险因素(P<0.05);观察组SF-36生理功能、生理职能、躯体疼痛、总体健康、生命活力、社会功能、情感职能、精神健康均低于对照组,差异有统计学意义(P<0.05)。结论肝胃郁热证、中虚气逆证、气郁痰阻证是胃食管反流病常见的中医证型,饮酒、高脂食物、便秘、进食过饱、精神紧张是胃食管反流病的高危因素,临床应重点关注具备该类高危因素的患者。
Objective To explore the influencing factors of gastroesophageal reflux disease and its TCM syndromes distribution.Methods One hundred patients with gastroesophageal reflux disease admitted to the Hospital from May 2018 to May 2019 were enrolled in the study group.Another 120 healthy subjects who had taken physical examinations during the same period were selected as the control group.TCM syndrome classification was performed in the study group,and their related factors were analyzed.Univariate analysis and logistic regression analysis were performed on the influencing factors of gastroesophageal reflux disease,and the quality of life in the two groups was compared.Results In the study group,there were 32 cases of liver and stomach stagnation syndrome,39 cases of Qi deficiency syndrome,25 cases of Qi stagnation syndrome,3 cases of liver heat stagnation syndrome,and 1 case of phlegm and blood stasis syndrome.Qi deficiency syndrome and Qi stagnation syndrome were predominant in female patients,and the syndrome of Qi deficiency was more common in patients over 60 years old,whose disease duration was longer than that of liver and stomach stagnation syndrome and Qi stagnation syndrome(P<0.05).Univariate analysis showed the difference between the two groups was statistically significant in terms of alcohol consumption,high-fat diet,constipation,overeating,and mental stress(P<0.05),and no significant difference in terms of gender,age,high-salt diet,and coffee consumption(P>0.05).Logistic regression analysis showed that alcohol consumption,high-fat diet,constipation,and overeating and mental stress were independent risk factors for gastroesophageal reflux disease(OR>l,P<0.05).The scores of SF-36 physiological function,physiological function,physical pain,general health,vitality,social function,emotional function and mental health in the study group were shown to be lower than the control group,and the difference was statistically significant(P<0.05).Conclusion Liver and stomach stagnation syndrome,Qi deficiency syndrome and Qi stagnation syndrome are common TCM syndromes of gastroesophageal reflux disease.Alcohol consumption,high-fat diet,constipation,and overeating and mental stress are high-risk factors for gastroesophageal reflux disease,and clinical treatment should focus on these high-risk factors.
出处
《浙江临床医学》
2021年第3期390-392,共3页
Zhejiang Clinical Medical Journal
关键词
胃食管反流病
流行病学
中医证型
危险因素
Gastroesophageal Reflux
Disease
Epidemiology
TCM Syndrome
Risk Factors
