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复方胞二磷胆碱注射液治疗青光眼视神经萎缩的效果研究

Study on the effect of compound citicoline injection on glaucoma optic nerve atrophy
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摘要 目的对青光眼视神经萎缩患者应用复方胞二磷胆碱注射液治疗的效果进行研究。方法样本选取在我科住院治疗的,符合纳入和排除标准的青光眼视神经萎缩患者,共计134例,分为参照组(采纳复方樟柳碱注射液治疗)和治疗组(采纳复方胞二磷胆碱注射液治疗)各67例,对比两组的治疗效果。结果就治疗总有效率而言,治疗组患者为89.55%,显著高于参照组患者的67.16%,χ^(2)=9.548,P=0.000,有统计学意义;就治疗后的视野光敏度、缺损度而言,观察组均显著优于参照组,P<0.05,有统计学意义;就视力水平、视野/MD、视觉诱发电位振幅以及P100潜时等指标而言,治疗组患者均明显优于参照组,t=8.542,10.257,5.998,6.365;P<0.05,有统计学意义。结论青光眼视神经萎缩患者应用复方胞二磷胆碱注射液治疗的效果确切,值得推广。 Objective To study the effect of compound cytidine choline injection in the treatment of glaucoma optic atrophy.Methods A total of 134 patients with glaucoma optic nerve atrophy who were hospitalized in our department and met the inclusion and exclusion criteria were selected and divided into the reference group(compound camphor injection)and the treatment group(compound cytiophosphorylcholine injection),67 patients each.The therapeutic effects of the two groups were compared.Results In terms of the total effective rate,89.55%in the treatment group,significantly higher than 67.16%in the control group,χ^(2)=9.548,P=0.000,which was statistically significant.In terms of visual field light sensitivity and defect degree after treatment,the observation group was significantly better than the control group,with P<0.05,which was statistically significant.In terms of visual acuity,visual field/MD,visual evoked potential amplitude,and P100 latent period,the treatment group was significantly better than the control group(T=8.542,10.257,5.998,6.365).P<0.05 was statistically significant.Conclusion Compound ciTIColine injection is effective in the treatment of glaucomatous optic nerve atrophy and is worth popularizing.
作者 张彤 ZHANG Tong(3201 hospital Hanzhong,Hanzhong,Shanxi 723000,China)
机构地区 三二〇一医院
出处 《中国国境卫生检疫杂志》 CAS 2020年第S01期56-57,62,共3页 Chinese Journal of Frontier Health and Quarantine
关键词 复方胞二磷胆碱注射液 青光眼 视神经萎缩 Compound cytosine diphosphate choline injection Glaucoma Optic atrophy
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