摘要
目的观察经纤维支气管镜灌洗清开灵口服液治疗重症肺炎(痰热壅肺证)的临床疗效。方法将70例重症肺炎(痰热壅肺证)患者随机分为治疗组与对照组两组各35例。两组均予西医常规治疗,对照组采用经纤维支气管镜灌洗0.9%氯化钠注射液治疗,治疗组采用经纤维支气管镜灌洗清开灵口服液治疗。两组均治疗2周。结果两组治疗后咳嗽评分、咯痰评分、喘息评分、白细胞(WBC)计数、C反应蛋白(CRP)、降钙素原(PCT)、动脉二氧化碳分压(PaLCO2)较治疗前降低(P<0.05),且治疗后治疗组低于对照组(P<0.05);两组治疗后包括动脉血氧分压(PaO2)、血氧饱和度(SaO2)较治疗前升高(P<0.05),且治疗后治疗组高于对照组(P<0.05);治疗组总有效率高于对照组(P<0.05)。结论经纤维支气管镜灌洗清开灵口服液治疗重症肺炎(痰热壅肺证),可显著改善临床症状及呼吸功能,抑制炎症因子表达,提高临床疗效。
Objective:To observe the clinical efficacy of Qingkailing Oral Liquid lavag’e through fiberoptic bronchoscope in the treatment of severe pneumonia(syndrome of phlegm-heat obstructing the lung).Methods:Seventy patients with severe pneumonia(syndrome of phlegm-heat obstructing the lung)were randomly divided into two groups,35 cases in each group.Both groups were treated with western medicine.The control group was treated with 0.9%sodium chloride injection by fiberoptic bronchoscope,and the treatment group was treated with Qingkailing Oral Liquid by fiberoptic bronchoscope.Both groups were treated for 2 weeks.Results:The cough score,cough score,wheezing score,WBC,CRP,PCT and PaCO2 of the two groups were lower than those before treatment(P<0.05),and the results in the treatment group were lower than those of the control group(P<0.05).The PaO2 and SaO2 were increased in both groups after treatment(P<0.05),and the results in the treatment group were higher than those of the control group(P<0.05).The total effective rate of the treatment group was higher than that of the control group(P<0.05).Conclusion:Treatment of severe pneumonia(syndrome of phlegm-heat obstructing the lung)by fiberoptic bronchoscopic lavage of Qingkailing Oral Liquid can significantly improve clinical symptoms and respiratory function,inhibit the expression of inflmmatorV factors,and improve clinical efficacy.
作者
李春
范铁兵
赵丹
易亮
肖宁
宁秋萍
Li Chun;Fan Tiebing;Zhao Dan;Yi Liang;Xiao Ning;Ning Qiuping(Xiyuan Hospital of China Academy of Chinese Medical Sciences,Beijing 100091,China.)
出处
《中国中医急症》
2021年第2期244-245,252,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
国家中医药管理局“十二五”重点专科建设项目(国中医药医政发[2012]2号)
北京市中医管理局中医住院医师规范化培训三优教学团队项目(市中医科字[20171]25号)。
关键词
重症肺炎
痰热壅肺证
纤维支气管镜
清开灵口服液
灌洗
临床观察
Severe pneumonia
Syndrome of phlegm-heat obstructing the lung
Fiberoptic bronchoscopy
Qingkailing Oral Liquid
Lavage
Clinical observation
