摘要
目的探讨体检人群幽门螺杆菌(Hp)感染状况,分析其影响因素,为制定Hp感染防护措施提供依据。方法采用简单随机抽样方法对2018年6月至2019年5月期间在北京市某医院体检中心进行健康体检人群进行抽样,对抽中的人群进行问卷调查、尿素[13C]散剂呼气试验和血生化指标检测。采用描述流行病学分析方法对该人群Hp感染情况进行分析,并采用单、多因素分析方法对Hp感染影响因素进行分析。结果本研究共对1058名体检人群进行调查,调查人群中男女性别比为1∶0.9,年龄以30~59岁为主,占45.94%,文化程度以高中/中专为主,占38.00%。检出Hp阳性者338例,阳性率为31.95%。多因素Logistic回归分析结果显示,年龄越大(OR=3.097)、同型半胱氨酸(Hcy)异常(OR=3.662)、有饮酒习惯(OR=4.484)者Hp阳性风险越大,Hp知识认知水平高者(OR=0.163)Hp阳性检出风险越小。结论该体检人群Hp阳性检出率较高,年龄、饮酒行为、Hp知识水平、Hcy异常等与Hp感染有关,应根据人群感染特征制定相应防护措施,降低Hp感染风险。
Objective To investigate the status of Helicobacter pylori(Hp)infection in the physical examination population,clarify its influencing factors,and provide reference information for clinical prevention and treatment of Hp infection.Methods A simple random sampling method was used to sample the physical examination population in the medical examination center of a hospital in Beijing from June 2018 to May 2019.Questionnaire survey,urea[13C]powder breath test and blood biochemical index detection were conducted among the selected population.Descriptive epidemiological analysis was used to analyze the Hp infection in this population,and the influencing factors were analyzed by univariate and multivariate analysis.Results A total of 1058 physical examination populations were surveyed.The male-to-female ratio in the survey population was 1∶0.9.The age group was mainly 30-59 years old,accounting for 45.94%,and the education level was mainly high school/secondary specialized school,accounting for 38.00%.Among them,338 cases of Hp positive were detected,and the positive rate was 31.95%.Multivariate logistic regression analysis showed that the older the age(OR=3.097),Hcy abnormality(OR=3.662),the drinking habit(OR=4.484),the greater the risk of Hp positive;and the higher the level of Hp knowledge(OR=0.163),the lower the risk of Hp positive.Conclusion The Hp infection rate in the physical examination population is relatively high.Age,drinking,lack of knowledge about Hp,Hcy abnormality,etc.are related to Hp infection.Corresponding protective measures should be formulated according to the characteristics of human infection to reduce the risk of Hp infection.
作者
崔文伟
王凯
梁璐
郭文芳
CUI Wen-wei;WANG Kai;LIANG Lu;GUO Wen-fang(Civil Aviation General Hospital,Beijing 100123,China)
出处
《华南预防医学》
2020年第6期613-616,共4页
South China Journal of Preventive Medicine
