摘要
在微生物源农药活性天然产物的筛选过程中,得到1株除草真菌NBERC51984,为明确其除草活性物质基础,对其次生代谢产物进行研究。通过活性跟踪以及菌株大量发酵,经提取和制备高效液相色谱分离纯化得到2个化合物,并通过LC-MS以及NMR鉴定为Pseurotin A(1)和Bisdethiobis(methylthio)gliotoxin(2),除草活性测试表明,化合物1对反枝苋具有生长抑制作用。
In the search for pesticides of natural products from microbes,fungus NBERC_51984 with herbicidal activity was obtained.In order to clarify the active substance basis of fungus NBERC_51984,its secondary metabolites were studied.By activity tracking and large-scale fermentation,2 compounds were isolated and identified as Pseurotin A(1)and Bisdethiobis(methylthio)gliotoxin(2)by LC-MS and NMR.Pseurotin A was found to show herbicidal activity to Amaranthus retroflexus.
作者
吴兆圆
张志刚
张亚妮
刘芳
方伟
WU Zhao-yuan;ZHANG Zhi-gang;ZHANG Ya-ni;LIU Fang;FANG Wei(Hubei Biopesticide Engineering Research Centre,Wuhan 430064,China)
出处
《湖北农业科学》
2020年第24期110-113,共4页
Hubei Agricultural Sciences
基金
国家重点研发计划项目[2017YFD0201301-4]
湖北省农业科技创新中心[2019-620-000-001-27]。
