摘要
目的:探讨肾移植术后感染的细菌分布及耐药性特点,为肾移植术后感染的合理用药提供依据。方法:收集医院诊治的187例肾移植术后感染患者痰、尿液等标本进行细菌培养、菌种鉴定和药敏试验。结果:培养阳性的337株致病菌中,痰液170株、尿液76株、引流液61株、血液24株、其他6株,主要阳性菌株是肺炎克雷伯杆菌、铜绿假单胞菌、表皮葡萄球菌等。敏感率较高的抗生素有万古霉素、亚胺培南、阿米卡星和头孢他啶等,耐药率较高的有青霉素、氨苄西林、哌拉西林等。结论:肾移植术后感染致病菌种以革兰阴性菌为主,肺炎克雷伯菌为主要致病菌,耐药性较高。
Objective:To provide a basis for the rational use of drugs for clinical treatment of infections after renal transplantation by understanding the distribution of bacteria and the characteristics of drug resistance after renal transplantation.Methods:Sputum and urine samples of 187 patients with infection after renal transplantation in the Renal Transplantation Ward of the Hospital were collected for bacterial culture,strain identification and drug sensitivity test.Results:Among the 337 strains of pathogenic bacteria with positive culture,170 strains were sputum,76 strains were urine,61 strains were drainage,24 strains were blood,and 6 strains were other strains.The main positive strains were Klebsiella pneumoniae,Pseudomonas aeruginosa,Staphylococcus epidermidis and so on.The antibiotics with higher sensitive rates were vancomycin,imipenem,amikacin and ceftazidime,and the higher resistance rates were penicillin,ampicillin,piperacillin and so on.Conclusion:The main pathogenic bacteria of infection after renal transplantation were Gram-negative bacteria.Klebsiella pneumoniae was the main pathogenic bacteria,and the drug resistance was high.
作者
杨璟
廖贵益
YANG Jing;LIAO Gui-yi(The First Affiliated Hospital of Anhui Medical University,Hefei 230022,Anhui)
出处
《安徽卫生职业技术学院学报》
2020年第6期90-92,共3页
Journal of Anhui Health Vocational & Technical College
关键词
肾移植
感染
耐药性
细菌
kidney transplantation
infection
drug resistance
bacteria
