摘要
黄连阿胶汤抗焦虑临床研究主要以黄连阿胶汤加减结合西药基础治疗,针对心肾不交型广泛性焦虑或阴虚火旺型继发性焦虑患者进行疗效观察,多认为本方可有效改善患者焦虑状态,并具有远期疗效好、不良反应发生率低、复发率低的优势。但研究中也存在一定不足,如在广泛性焦虑的研究中,多数临床观察的中医辨证分型并无权威标准,部分纳入标准对广泛性焦虑和惊恐障碍划分不明确,且广泛性焦虑病程持续,研究中对药物长期疗效、疾病复发率的观察明显不足;在焦虑综合征的研究中,对于焦虑症状的诊断标准往往较为模糊,焦虑改善情况的评定标准并不统一,且针对药物安全性的评价有所欠缺,对该方抗焦虑作用机制的研究亦不完善。
At present,the clinical research of Huanglian-Ejiao Decoction for anti-anxiety mainly focuses on the treatment of western medicine combined with the addition and subtraction of Huanglian-Ejiao Decoction.By observing the generalized anxiety patients with heart kidney disharmony or secondary anxiety symptoms of yin deficiency and fire hyperactivity type after taking Huanglian-Ejiao Decoction,all the studies show that this prescription can effectively improve the anxiety state of patients,and has long-term effect,low incidence of adverse reactions and low recurrence rate.However,there are also some deficiencies in the study,such as in the study of generalized anxiety,most clinical observation of TCM syndrome differentiation has no authoritative standard,some of the inclusion criteria for generalized anxiety and panic disorder are not clear,and the course of generalized anxiety is persistent,the observation of long-term efficacy and recurrence rate of diseases is obviously insufficient;in the study of anxiety syndrome,for anxiety disorder The diagnostic criteria of the disease are often not clear,the evaluation criteria of anxiety improvement are not unified,and there lacks the evaluation of safety.At the same time,the mechanism research on Huanglian-Ejiao Decoction is not perfect.
作者
邢婧瑜
王惠君
袁红霞
Xing Jingyu;Wang Huijun;Yuan Hongxia(Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;College of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;College of Management,Tianjin University of Traditional Chinese Medicine,Tianjin 301617)
出处
《国际中医中药杂志》
2020年第11期1151-1154,共4页
International Journal of Traditional Chinese Medicine
关键词
黄连阿胶汤
抗焦虑药(中药)
情志内伤
阴虚火旺
心肾不交
综述
Huang Lian E Jiao Tang
Anti-anxiety drugs(TCD)
Seven emotions stimulating
Yin deficiency fire hyperactivity
Syndrome of disharmony between heart and kidney
Review
