摘要
目的通过对肺癌死亡特征定量研究及潜在减寿分析,为肺癌综合防控提供科学依据。方法分析常州市武进区2004—2019年肺癌粗/标化死亡率、年龄别死亡特征,运用差别分解分析法定量分析肺癌死亡影响因素,计算年度变化百分比(APC)及其95%CI、潜在寿命损失等相关指标。结果2004—2019年武进区肺癌平均粗/标化死亡率分别为43.80/10万、22.03/10万,粗死亡率呈逐年上升趋势[APC(95%CI)为4.50%(3.34%~5.68%),P<0.001],在恶性肿瘤死因中的构成比呈逐年上升趋势[APC(95%CI)为3.04%(2.30%~3.77%),P<0.001]。肺癌死亡率在30岁前处于较低水平,30~<70岁、≥70岁组男性、女性及合计的肺癌死亡率均呈现逐年上升趋势(P值均<0.05)。与2004年相比,2019年肺癌死亡率上升了21.56/10万,人口与非人口因素的贡献率分别为91.25%、8.75%;男性中非人口因素有导致肺癌死亡率下降作用。肺癌所致平均寿命损失年数(AYLL)为9.57年,男性、女性、合计AYLL均呈逐年下降趋势[APC(95%CI)为-2.28%(-3.02%^-1.53%)、-1.10%(-1.95%^-0.25%)、-1.90%(-2.59%^-1.20%),P值均<0.05]。结论常州市武进区2004—2019年肺癌粗死亡率逐年上升,已上升为恶性肿瘤中首位死因,老龄化为主要原因,应加强肺癌综合防治工作。
Objective To conduct a quantitative study on the characteristics of lung cancer mortality and potential years of life loss(PYLL);to provide scientific basis for comprehensive prevention and control of lung cancer.Methods The crude/standardized mortality rates and death characteristic of lung cancer by age groups from 2004 to 2009 in Wujin district of Changzhou city were analyzed.Differential decomposition analysis was used to quantitatively analyze the influential factors of lung cancer death,and relevant indicators such as annual percentage change(APC)and its 95%CI together with potential years of life loss were calculated.Results From 2004 to 2019,the average crude/standardized mortality rates of lung cancer were43.80/105 and 22.03/105,respectively;the crude mortality rate and the composition ratio of malignant tumor causing death both showed ascending trend(APC=4.50%,95%CI:3.34%-5.68%;APC=3.04%,95%CI:2.30%-3.77%,all P<0.001).The mortality rate of lung cancer was at a low level for residents younger than 30 years old.The mortality rates of residents in age group of 30-70 years old,males older than 70 years,females and total lung cancer demonstrated ascending trend year by year(all P<0.05).Compared with 2004,the mortality rate of lung cancer in 2019 increased by 21.56/105,the contribution of demographic and non-demographic factors accounted for 91.25%and 8.75%,respectively;and in the males,non-demographic factors were associated with reduced lung cancer mortality rate.The average years of life loss(AYLL)was 9.57 years.The trend of AYLL caused by lung cancer in males,females and total all showed descending trend year by year[APC(95%CI):-2.28%(-3.02%,-1.53%),-1.10%(-1.95%,-0.25%),-1.90%(-2.59%,-1.20%),all P<0.05].Conclusion From 2004 to 2019,the crude mortality rate of lung cancer in Wujin district of Changzhou city increased year by year,and becomes the top 1 cause of death among malignant tumors.Aging was the main factor,comprehensive prevention and treatment for lung cancer should be strengthened.
作者
强德仁
石素逸
许敏锐
宗菁
杨佳成
潘英姿
QIANG De-ren;SHI Su-yi;XU Min-rui;ZONG-Jing;YANG Jia-cheng;PAN Ying-zi(Wujin District Center for Disease Control and Prevention,Jiangsu Changzhou 213164,China)
出处
《江苏预防医学》
CAS
2020年第6期614-617,共4页
Jiangsu Journal of Preventive Medicine
基金
国家重点研发计划(2017YFC0907002)
常州市武进区科技支撑计划(社会发展)项目(WS201829)。
关键词
肺癌
死亡率
差别分解法
年度变化百分比
减寿分析
Lung cancer
Mortality rate
Differential decomposition
Annual percentage change
Potential years of life lost analysis
