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大剂量瑞舒伐他汀治疗老年冠心病并高脂血症的效果及安全性分析 被引量:2

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摘要 目的分析大剂量瑞舒伐他汀治疗老年冠心病并高脂血症的效果及安全性。方法 104例老年冠心病并高脂血症患者,根据治疗药物的剂量不同分为观察组和对照组,各52例。对照组采用小剂量瑞舒伐他汀治疗,观察组采用大剂量瑞舒伐他汀治疗。比较两组患者治疗前后血脂水平[总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)]、治疗效果、并发症发生情况。结果治疗后,观察组患者TC(4.10±0.94)mmol/L、TG(1.29±0.83)mmol/L、LDL-C(2.11±0.43)mmol/L均低于对照组的(5.17±0.82)、(1.89±0.76)、(3.10±0.80)mmol/L, HDL-C(0.98±0.12)mmol/L高于对照组的(0.81±0.37)mmol/L,差异均具有统计学意义(P<0.05)。观察组治疗总有效率94.23%高于对照组的80.77%,差异具有统计学意义(P<0.05)。观察组并发症发生率5.77%与对照组3.85%,差异无统计学意义(P>0.05)。结论大剂量瑞舒伐他汀能更好地控制冠心病并高脂血症老年患者的血脂水平,且并发症少,安全性高,值得应用。
出处 《中国实用医药》 2020年第35期133-135,共3页 China Practical Medicine
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