摘要
目的探讨槐杞黄颗粒治疗肝癌TACE术后患者的临床疗效。方法选取本院肝癌TACE术后患者90例,分为实验组60例与对照组30例。实验组给予常规护肝+槐杞黄颗粒治疗,对照组给予常规护肝治疗。两组均治疗4周后评定治疗效果。结果治疗结束后,两组各症状较治疗前明显好转,且实验组改善情况优于对照组(P<0.05);实验组肝郁脾虚证、脾虚湿困证,肝肾阴虚证各证总有效率均高于对照组(P<0.05);实验组各证型间疗效比较,差异无统计学意义(P>0.05)。实验组总有效率明显高于对照组(P<0.05)。实验组生活质量(KPS)评分总提高率高于对照组(P<0.05)。两组患者在治疗期间均未出现药物不良反应。结论槐杞黄颗粒治疗肝癌TACE术后肝郁脾虚证、脾虚湿困证、肝肾阴虚证效果确切,且无明显不良反应,值得推广应用。
Objective To explore the clinical efficacy of Huaiqihuang Granules in the treatment of patients with liver cancer after TACE.Methods A total of 90 patients with liver cancer after TACE in our hospital were divided into the experimental group(n=60)and the control group(n=30).The 60 patients in the experimental group were treated with conventional liver protection plus Huaiqihuang Granules,while the control group was treated with conventional liver protection.In both groups,the curative effect was evaluated after 4 w of treatment.Results After the ending of treatment,the symptoms of the two groups were significantly better than before,and the improvement in the experimental group was better than that in the control group(P<0.05).The total effective rates of treatment of the syndrome of liver depression and spleen deficiency,the syndrome of Pi-deficiency with damp harassment,the syndrome of the liver and kidney yin deficiency in the experimental group were all higher than those in the control group(P<0.05).There was no statistically significant difference in efficacy among syndrome types of the experimental group(P>0.05).The total effective rate in the experimental group was significantly higher than that in the control group(P<0.05).The total improvement rate of Karnofsky performance scale(KPS)scores in the experimental group was higher than that in the control group(P<0.05).No adverse reactions to drugs occurred among the patients of the two groups during treatment.Conclusion Huaiqihuang Granules have definite efficacy in treating the syndrome of liver depression and spleen deficiency,the syndrome of Pi-deficiency with damp harassment,and the syndrome of the liver and kidney yin deficiency after TACE for liver cancer,and they don't incur any obvious adverse reactions.They are worthy of promotion and application.
作者
胡铧东
沈亚
魏大海
陆许贞
HU Huadong;SHEN Ya;WEI Dahai;LU Xuzhen(Department of Infection Control,the First Hospital of Jiaxing City in Zhejiang Province,Jiaxing314000,China)
出处
《中国现代医生》
2020年第31期12-14,18,共4页
China Modern Doctor
基金
浙江省自然科学基金项目(LY20C010004)
浙江省嘉兴市科技计划项目(2018AD32097)。
关键词
槐杞黄颗粒
肝癌TACE术后
临床疗效
中医证型
Huaiqihuang Granules
Liver cancer after TACE
Clinical efficacy
Syndrome types of traditional Chinese medicine
