摘要
雌三醇是哺乳动物体内重要的性激素,由卵巢产生和分泌的雌二醇和雌酮经生物转化而来。雌三醇临床上可用于雌激素缺乏症以及辐射损伤的治疗。雌三醇的含量检测和分析对于食品、环境监测和人类健康越来越重要。本文综述了雌三醇的含量检测方法,按血浆、血清、尿液、唾液、废水等不同基质进行分类,从样品基质、前处理方法、使用仪器等方面来进行阐述,为雌三醇的检测方法选择提供参考依据。
Estriol is an important sex hormone in mammals,which is produced and secreted by the ovary through biological transformation from estradiol and estrone.Estriol can be used in the treatment of estrogen deficiency and radiation injury.The detection and analysis of estriol content are becoming more and more important for food,environmental monitoring and human health.There⁃fore,this paper summarizes the methods for the detection of estriol content,classifying them in terms of the different substrates such as plasma,serum,urine,saliva and waste water,and expounds them from the aspects of sample substrates,pretreatment methods and instruments,so as to provide reference for choosing detection methods for estriol.
作者
张汉铭
孟志云
朱晓霞
顾若兰
吴卓娜
李俭
甘慧
窦桂芳
ZHANG Han-ming;MENG Zhi-yun;ZHU Xiao-xia;GU Ruo-lan;WU Zhuo-na;LI Jian;GAN Hui;DOU Gui-fang(Institute of Radiation Medicine,Academy of Military Medical Sciences,Academy of Military Sciences,Beijing 100850,China)
出处
《国际药学研究杂志》
CAS
北大核心
2020年第11期962-966,共5页
Journal of International Pharmaceutical Research
基金
北京市自然科学基金面上项目(7202148)。
关键词
雌三醇
检测
方法学
estriol
detection
methodology
