摘要
A型肉毒毒素在20世纪80年代中期首次在医学美容中使用,常用来治疗面颈部皱纹,随着研究的深入,发现A型肉毒毒素对其他疾病也有干预作用。该文回顾近年来相关文献,总结A型肉毒毒素的作用机制,并分析其在整形外科非常规美容治疗领域的应用,包括阻断支配汗腺的神经从而治疗腋臭、抑制胸大肌的活动以增加自体脂肪隆胸术的脂肪移植存活率、改善手部慢性血管痉挛性疾病的血流速度、提高皮瓣存活率、抑制成纤维细胞增殖而改变伤口的外观、缓解疼痛、减少皮脂腺分泌改善痤疮、减轻体重等。
Since botulinum toxin type A was first used in medical cosmetology in the mid-1980s,it has been commonly used to treat facial and neck wrinkles.In recent years,it has been found that botulinum toxin type A also has an intervention effect on other diseases.This article reviewed the related literatures in recent years.We also summarized the mechanismof botulinum toxin type A and analyzes its application in the field of unconventional cosmetic treatment of plastic surgery,including blocking the nerves that innervate sweat glands to treat axillary odor;inhibiting the activity of the pectoralis major to increase fat graft survival rate after autologous fat breast augmentation.It has improvement effect on blood flow rate of chronic vasospasm disease of hand and flap survival rate.It can also inhibit fibroblast proliferation and change the appearance of wound;relieve pain;reduce sebaceous gland secretion and improve acne;as well as relieve body weight.
作者
逄浩
肖志波
Pang Hao;Xiao Zhibo(The Second Affiliated Hospital of Harbin Medical University,Harbin 150000,China)
出处
《中华整形外科杂志》
CAS
CSCD
北大核心
2020年第9期1053-1057,共5页
Chinese Journal of Plastic Surgery
