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去骨瓣减压术后颅骨缺损合并早期脑积水的发生机制及手术治疗研究进展 被引量:10

Research Progress in Mechanism and Surgical Treatment of Skull Defects Combined with Early Hydrocephalus after Decompression Craniectomy
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摘要 去骨瓣减压术是神经外科急诊中的常用术式,但因其破坏了颅脑正常生理结构,不可避免地会引起很多术后并发症。颅骨缺损合并早期脑积水是其中较常见的并发症,会导致脑组织软化、脑血流动力学改变、脑脊液压力不稳定、蛛网膜颗粒损伤等病理生理改变,对神经功能造成重大损害。目前,治疗颅骨缺损合并早期脑积水的常用手术方式为颅骨修补术(CP)及脑室腹腔分流术(VPS),但两者的手术时机没有达成共识。对于颅骨缺损合并脑积水患者同期行CP及VPS相较分期手术疗效更好,可减轻患者的经济负担和压力,且并发症较少,是一种切实可行的治疗手段。 Decompressive craniectomy is a common operation in the emergency department of neurosurgery,but due to its destruction of the normal physiological structure of the brain,it will inevitably cause many postoperative complications.Skull defect combined with early hydrocephalus is a common complication,which may lead to pathophysiological changes such as brain tissue softening,cerebral hemodynamic change,cerebrospinal fluid pressure instability,and arachnoid particle injury,causing significant damage to the nerve function.At present,the commonly used surgical methods for the treatment of skull defect combined with early hydrocephalus are cranioplasty(CP)and ventriculoperitoneal shunt(VPS),but there is no consensus on the surgical timing.For patients with skull defects combined with hydrocephalus,concurrent CP and VPS are more effective than staged operation,which can reduce the patients′economic burden and pressure,with fewer complications,and is a feasible treatment method.
作者 金陆昊 孙晓阳 JIN Luhao;SUN Xiaoyang(Department of Neurosurgery,the Affiliated Huai′an N0.1 People′s Hospital of Nanjing Medical University,Huai′an 223000,China)
出处 《医学综述》 2020年第23期4704-4709,共6页 Medical Recapitulate
关键词 颅脑损伤 早期脑积水 去骨瓣减压术 颅骨修补术 脑室腹腔分流术 Craniocerebral injury Early Hydrocephalus Decompressive craniectomy Cranioplasty Ventriculoperitoneal shunt
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