摘要
目的:探讨对抑郁伴睡眠障碍患者采用曲唑酮治疗的效果及对其睡眠质量的影响。方法:选取2017年10月至2019年10月期间福建省立医院收治的抑郁伴睡眠障碍患者100例作为研究对象,按照随机数字表法分为对照组和观察组,每组50例。对照组治疗药物为阿普唑仑,观察组治疗药物为曲唑酮,分析治疗效果、治疗前后HAMD评分以及PSQI评分。结果:观察组总有效率较对照组高,HAMD评分、PSQI评分较对照组低(P<0.05)。结论:对抑郁伴睡眠障碍患者采用曲唑酮治疗效果较好,可有效减轻抑郁程度,改善抑郁状况,提高睡眠质量。
Objective:To explore the effect of Trazodone in the treatment of depression with sleep disorders and its effect on sleep quality.Methods:A total of 100 patients with depression and sleep disorder were enrolled from October 2017 to October 2019.They were divided into two groups according to the random number table.The control group(n=50)was treated with alprazolam and the observation group(n=50)was treated with trazodone.The therapeutic effect,HAMD score and PSQI score before and after treatment were analyzed.Results:The total effective rate of the observation group was higher than that of the control group,and the scores of HAMD and PSQI were lower than that of the control group(P<0.05).Conclusion:Trazodone is effective in the treatment of depression with sleep disorder.It can effectively reduce the degree of depression,improve the state of depression and improve the quality of sleep.
作者
吴丹
WU Dan(Fujian Provincial Hospital,Fuzhou 350001,China)
出处
《世界睡眠医学杂志》
2020年第10期1722-1723,共2页
World Journal of Sleep Medicine
关键词
抑郁
睡眠障碍
曲唑酮
睡眠质量
Depression
Sleep disorders
Trazodone
Sleep quality
