摘要
目的研究睡眠呼吸暂停低通气综合征患者(SAHS)合并心律失常的危险因素。方法对焦作市人民医院2017年6月至2019年6月收治的睡眠呼吸暂停低通气综合征患者68例进行回顾性分析总结,并根据患者是否合并心律失常进行分组。其中32例患者未合并心律失常作为对照组,36例患者合并心律失常作为心律失常组。采用单因素分析和Logistic多因素分析对导致患者出现心律失常的危险因素进行分析。结果本研究68例SAHS患者合并心律失常者共36例,发生率为52.94%(36/68)。单因素分析结果显示,患者饮酒史、BMI、左房大小、超氧化物歧化酶1(SOD1)、诱导型一氧化氮合酶(iNOS)、肿瘤坏死因子-α(TNF-α)、三酰甘油、总胆固醇等因素均是导致SAHS患者出现心律失常的的主要因素(P<0.05)。经Logistic多因素方差分析结果显示,患者BMI指数、左房大小以及iNOS水平是导致SAHS患者发生心律失常的高危因素(P<0.05)。结论SAHS患者合并心律失常的比率较高,且导致SAHS患者出现心律失常的危险因素较多,其中BMI指数,左房大小以及iNOS水平是导致SAHS患者合并心律失常的独立危险因素。
Objective To study the risk factors of patients with sleep apnea hypopnea syndrome(SAHS)complicated with arrhythmia.Methods Sixty-eight patients with sleep apnea hypopnea syndrome admitted to Jiaozuo People's Hospital from June 2017 to June 2019 were retrospectively analyzed and summarized,and they were grouped according to whether the patients were complicated with arrhythmia.Among them,32 patients without heart rhythm arrhythmia was included as the control group,and 36 patients with arrhythmia were included as the arrhythmia group.Univariate analysis and Logistic multivariate analysis were used to analyze the risk factors leading to arrhythmia.Results A total of 36 SAHS patients with arrhythmia were included in this study,with an incidence of 52.94%(36/68).Univariate analysis showed that the drinking history,BMI,left atrium size,SOD1,iNOS,TNF-α,triglyceride,total cholesterol were the main factors that cause arrhythmia in SAHS patients(P<0.05).Logistic multivariate analysis of variance showed that BMI index,left atrium size,and iNOS level were the high-risk factors for arrhythmia in SAHS patients(P<0.05).Conclusions The rate of SAHS patients with arrhythmia is high,and there are many risk factors for arrhythmia in SAHS patients.Among them,BMI index,left atrial size and iNOS level are independent risk factors for SAHS patients with arrhythmia.
作者
马琳
Ma Lin(Department of Cardiology,the People’s Hospital of Jiaozuo,Jiaozuo 454000,China)
出处
《临床医学》
CAS
2020年第10期20-23,共4页
Clinical Medicine
