摘要
目的探讨急性脑梗死合并颅内未破裂动脉瘤患者的危险因素及预后分析。方法急性脑梗死患者457例,其中45例合并颅内未破裂动脉瘤作为合并组;412例未合并颅内未破裂动脉瘤作为未合并组,收集患者的人口学特征、实验室检查和未破裂动脉瘤特征,采用多因素Logistic分析急性脑梗死合并颅内未破裂动脉瘤患者的危险因素及预后。结果2组性别比、平均年龄、平均BMI、卒中家族史、高血压病、吸烟史及血清FBG、TC、TG比较差异有统计学意义(P<0.05)。Logistic分析见性别、平均年龄、平均BMI、卒中家族史、高血压病、吸烟史与急性脑梗死合并颅内未破裂动脉瘤密切相关(P<0.05)。女性、年龄增大、BMI增大、有卒中家族史、有高血压病、吸烟史是急性脑梗死合并颅内未破裂动脉瘤高危因素(P<0.05)。预后不良组与预后好组动脉瘤瘤颈大小、直径及规则程度比较差异有统计学意义(P<0.05)。Logistic分析见瘤颈大小、规则程度与合并颅内未破裂动脉瘤急性脑梗死患者的早期预后密切相关(P<0.05)。瘤颈大、不规则是合并颅内未破裂动脉瘤急性脑梗死患者预后不良的高危因素(P<0.05)。结论女性、年龄和BMI增大、有卒中家族史、有高血压病、吸烟史是急性脑梗死合并颅内未破裂动脉瘤高危因素,瘤颈大小和形状规则程度与合并颅内未破裂动脉瘤患者的预后有关。
Objective To investigate the risk factors and prognosis in patients with acute cerebral infarction complicated by unruptured intracranial aneurysm.Methods A total of 457 patients with acute cerebral infarction who were treated in our hospital from January 2017 to January 2019 were enrolled in the study,of whom,the 45 patients with unruptured intracranial aneurysms were enrolled as complication group,and the other 412 patients without unruptured intracranial aneurysms were enrolled as non complication group.The demographic,laboratory and unruptured aneurysm characteristics of the patients were collected,and multivariate logistic analysis was used to analyze the risk factors and prognosis of patients with acute cerebral infarction complicated by unruptured intracranial aneurysm.Results There were significant differences in patients gender and age,BMI,family history of stroke,hypertension,smoking history and serum levels of FBG,TC,TG between the two groups(P<0.05).Logistic analysis showed that patient’s gender,average age,average BMI,stroke family history,hypertension,smoking history were closely related to the incidence of acute cerebral infarction complicated by unruptured intracranial aneurysm.Moreover female,age increasing,BMI increasing,family history of stroke,hypertension history and smoking history were the high risk factors of acute cerebral infarction complicated by nruptured intracranial aneurysm(P<0.05).There were differences in the size,diameter and regularity of aneurysm neck between poor prognosis group and good prognosis group(P<0.05).Logistic analysis showed that the size and regularity degree of tumor neck were closely related to the early prognosis of patients,and the larger and irregular tumor neck were high risk factors of poor prognosis of patients(P<0.05).Conclusion The females,age and BMI increasing,family history of stroke,hypertension history and smoking history are the high risk factors of incidence of acute cerebral infarction complicated by unruptured intracranial aneurysm.Moreover the size and shape of the tumor neck are related to the prognosis of patients with unruptured intracranial aneurysm.
出处
《河北医药》
CAS
2020年第22期3405-3408,共4页
Hebei Medical Journal
基金
河北省中医药管理局科研计划项目(编号:2020295)。
关键词
急性脑梗死
颅内未破裂动脉瘤
危险因素
预后
acute cerebral infarction
unruptured intracranial aneurysm
risk factors
prognosis
