摘要
目的总结18例儿童原发气管、支气管肿瘤病例的临床资料,探讨支气管镜介入诊疗的安全性和有效性。方法回顾性研究山东大学齐鲁儿童医院2013年1月至2019年8月收治的18例原发气管、支气管肿瘤患儿的临床表现、体征、影像学、支气管镜下表现、病理类型、内镜下介入治疗方法及转归,并加以分析。结果本组患儿年龄2~12岁;男女比例为1.71∶1;病理类型:黏液表皮样癌8例,炎性肌纤维母细胞瘤7例,婴幼儿纤维肉瘤1例,中间型血管肿瘤1例,腺泡细胞癌1例。18例患儿均在全麻下完成活检明确肿瘤病理类型,并通过介入治疗手段解除呼吸道梗阻。术中、术后未发生大出血、气胸、纵隔气肿等并发症。术后1周复查内镜评估疗效,完全有效17例,无效1例,总有效率94%。结论经支气管镜介入治疗原发气管、支气管肿瘤安全、有效,可作为姑息治疗手段,为进一步外科手术根治创造条件,甚至成为根治腔内肿瘤的治疗方法。
Objective To summarize the clinical data of 18 children with primary tracheobronchial tumors,and to investigate the safety and effectiveness of bronchoscopy intervention therapy.Methods The clinical features,signs,imaging and bronchoscope characteristics,pathology types,endoscopy intervention therapy methods,and outcomes of 18 patients with primary tracheobronchial tumors treated in Qilu Children's Hospital of Shandong University from January 2013 to August 2019 were retrospectively analyzed.Results The patients aged from 2 years old to 12 years old,and the ratio of male and female was 1.71∶1.There were 8 cases of mucoepidermoid carcinoma,7 cases of inflammatory myofibroblastoma,1 case of infant fibrosarcoma,1 case of intermediate vascular tumor,and 1 case of acinar cell carcinoma.All 18 patients received the biopsy under general anesthesia to determine the pathological type of tumor and underwent the interventional therapy to relieve airway obstruction.No complications such as massive bleeding,pneumothorax,and mediastinal emphysema were observed during and after operation.The endoscope examination was applied to assess the curative effect 1 week after the surgery,complete response 17 case,inefficiency 1 case,and the overall effective rate was 94%.Conclusions It is safe and reliable to treat primary tracheobronchial tumor by bronchoscopy intervention therapy,which can be used as a palliative treatment and create conditions for further radical operation.It may even become a radical cure for tracheobronchial tumors.
作者
王超
王少超
刘帅帅
王磊
李娟
吉金姗
孟晨
Wang Chao;Wang Shaochao;Liu Shuaishuai;Wang Lei;Li Juan;Ji Jinshan;Meng Chen(Center for Respiratory Intervention,Qilu Children's Hospital of Shandong University,Jinan 250022,China)
出处
《中华实用儿科临床杂志》
CSCD
北大核心
2020年第21期1643-1647,共5页
Chinese Journal of Applied Clinical Pediatrics
