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用血清甲胎蛋白和唾液酸联合检测法诊断原发性肝癌的效果分析

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摘要 目的:探讨用血清甲胎蛋白(AFP)和唾液酸(SA)联合检测法诊断原发性肝癌(PHC)的效果。方法:选取2019年3月至2020年2月期间某医院收治的111例PHC患者、122例肝良性病变患者及同期在该院进行体检的137例健康人作为研究对象。将111例PHC患者设为A组,将122例肝良性病变患者设为B组,将137例健康人设为对照组。对三组受检者均进行血清AFP和SA检测,比较其检测的结果。结果:A组患者血清AFP及SA的水平均高于B组患者和对照组健康人,P<0.05。B组患者血清AFP及SA的水平均高于对照组健康人,P<0.05。与用血清SA检测法诊断PHC相比,用血清AFP检测法诊断PHC的曲线下面积、正确诊断指数(YI)值均更大,特异性更高,灵敏度更低,P均<0.05。与用血清AFP、SA单项检测法诊断PHC相比,用血清AFP和SA联合检测法诊断PHC的曲线下面积、YI值均更大,灵敏度、特异性均更高,P均<0.05。结论:用血清AFP和SA联合检测法诊断PHC的效果较为理想。
出处 《当代医药论丛》 2020年第21期127-128,共2页
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  • 1Jong Young Choi,Seung Won Jung,Hee Yeon Kim,Myungshin Kim,Yonggoo Kim,Dong Goo Kim,Eun-Jee Oh.Diagnostic value of AFP-L3 and PIVKA-Ⅱin hepatocellular carcinoma according to total-AFP[J].World Journal of Gastroenterology,2013,19(3):339-346. 被引量:68
  • 2Lin Zhou,Jia Liu,Feng Luo.Serum tumor markers for detection of hepatocellular carcinoma[J].World Journal of Gastroenterology,2006,12(8):1175-1181. 被引量:79
  • 3张健 张炳昌 武春晓 等.血清唾液酸在三种临床常见恶性肿瘤中的检测及临床意义[J].医学检验与临床,2008,19:26-28.
  • 4Patel PS,Raval GN,Rawal RM,et al.Importance of glycoproteins in human cancer.Indian J Biochem Biophys,1997,34:226-233.
  • 5Hsu HC, Cheng W, Lai PL. Cloning and expression of adevelopmentally regulated transcript MXR7 in hepatocellular carcinoma: biological significance and temporo spatial distribution [ J]. Cancer Res,1997,57(22) :5179 -5184.
  • 6Nakatsura T, Yoshitake Y, Senju S, et al. Glypican - 3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker [ J]. Biochemical and Biophysical Research Communications, 2003,306 ( 1 ) : 16 - 25.
  • 7Pontisso P, Calabrese F, Benvegnu L, et al. Over expression of squamous cell carcinoma antigen variants in hepatocellular carcinoma [ J ].Br J Cancer,2004,90 ( 4 ) :833 - 837.
  • 8Beneduce L, Castaldi F, Marino M, et al. Squamous Cell Carcinoma Antigen - Immunoglobulin MComplexes as Novel Biomarkers for Hepatocellular Carcinoma [ J ]. Cancer,2005,103 ( 12 ) : 2558 - 2565.
  • 9Jenml A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin, 20ll ,61:69-90.
  • 10Zhao P, Dai M, Chen WQ, et al. Cancer trends in China. Jpn J Clin Onco1,2010,40:281-285.

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