摘要
目的建立火焰原子吸收光谱法测定山葡健脾颗粒中葡萄糖酸锌、滴定法测定枸橼酸含量的方法。方法火焰原子吸收光谱法测定锌元素含量,采用空气-乙炔火焰,锌元素测定波长213.9 nm,燃气流量0.9 L/min,燃烧器高度7.2 mm,背景校正:氘灯,通带宽度1.0 nm;以酚酞作为指示剂,氢氧化钠进行滴定,测定枸橼酸含量。结果山葡健脾颗粒中锌元素在0.1~2.0μg/ml范围内,线性关系良好(r=0.9998),平均回收率94.06%(RSD=1.67%),枸橼酸含量的平均回收率为94.65%(RSD=0.91%)。结论该方法简单、准确、灵敏度高,可用于山葡健脾颗粒中葡萄糖酸锌和枸橼酸含量的测定。
Objective To develop a method for the determination of Zinc gluconate and citric acid in Shanpu-Jianpi granule.Methods The air-acetylene was selected as flame type,the detection wavelength was 213.9 nm,the gas flow rate was 0.9 L/min,the burner height was 7.2 mm,and deuterium lamp was used as background correction.The width of passband was 1.0 nm.Titration,sodium hydroxide was used to determine the citric acid with phenolphthalein as an indicator.Results The content of Zinc Meletin,exhibited good linearity(r=0.9998)among the ranges of 0.1-2.0μg/ml and the average recovery was 94.06%(RSD=1.67%).The average recovery of citric acid was 94.65%(RSD=0.91%).Conclusions The method is simple,accurate and high sensitivity which can be used for determination of Zinc gluconate and citric acid in Shanpu-Jianpi granule.
作者
任伟伟
蔡建红
张月婵
陈晓菲
Ren Weiwei;Cai Jianhong;Zhang Yuechan;Chen Xiaofei(Zhangjiagang Hospital of Traditional Chinese Medicine,Affiliated Zhangjiagang Hospital of Nanjing University of Chinese Medicine,Zhangjiagang 215600,China)
出处
《国际中医中药杂志》
2020年第8期783-786,共4页
International Journal of Traditional Chinese Medicine
