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小剂量左旋甲状腺素治疗良性甲状腺结节的效果分析 被引量:2

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摘要 目的分析小剂量左旋甲状腺素治疗良性甲状腺结节的效果。方法 50例良性甲状腺结节患者,随机分为实验组和对照组,各25例。对照组采用常规治疗,实验组采用小剂量左甲状腺素钠片治疗。比较两组患者治疗前后甲状腺结节体积变化情况、甲状腺激素水平以及患者治疗满意度。结果治疗后,实验组患者甲状腺结节体积改善程度优于对照组,差异具有统计学意义(P<0.05)。治疗后,实验组患者促甲状腺激素、游离甲状腺激素、游离三碘甲状腺激素水平分别为(0.56±0.32)、(26.32±0.32)、(4.02±0.32)pmol/L,均优于对照组的(1.56±0.32)、(18.25±0.63)、(4.51±0.20)pmol/L,差异均具有统计学意义(P<0.05)。实验组患者治疗总满意度96.00%高于对照组的72.00%,差异具有统计学意义(χ^2=5.357, P<0.05)。结论小剂量左旋甲状腺素治疗良性甲状腺结节效果显著,能够改善患者相关指标,对患者自身治疗工作实施具有重要指导意义。
作者 王丹
机构地区 大连市友谊医院
出处 《中国现代药物应用》 2020年第20期96-97,共2页 Chinese Journal of Modern Drug Application
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  • 1Fagin JA, Mitsiades N. Molecular pathology of thyroid cancer: diagnostic and clinical im?plications [Jl. Best Pract Res Clin Endocri?nol Metah, 2008, 22 (6): 955 -969.
  • 2Papini E, Guglielmi R, Bianchini A, et al. Risk of malignancy in nonpalpahle thyroid nod?ules: predictive value of ultrasound and color - Doppler features [J]. J Clin Endocrinol Metah, 2002, 87 (5): 1941 -1946.
  • 3Iyer NG, Shaha AR. Management of thyroid nodules and surgery for differntiated thyroid cancer [J]. Clin Oncol (R Coil Radiol), 2010, 22 (6): 405 -412.
  • 4Alexander EK, Hurwitz S, Heering JP, et al. Natural history of benign solid and cystic thyroid nodules [J]. Ann Intern Med, 2003, 138 (4): 315 -318.
  • 5Gharib H. Fine needle aspiration biopsy of thyroid nodules: advantages, limitations and effect [J]. Mayo Clin Proc , 1994 , 69 (1): 44 -49.
  • 6Wojtczak B, Sutkowski K, Bolanowski M, et al. The prognostic value of fine - needle aspiration biopsy of the thyroid gland - analy?sis of results of 1078 patients [J]. Neuro Endocrinol Lett, 2012, 33 (5): 511 - 516.
  • 7Grussendorl M, Reiners C, Paschke R, et al. Reduction of thyroid nodule volume by levothyroxine and iodine alone and in combi?nation: a randomized, placebo - controlled trial [J]. J Clin Endocrinol Metab, 2011, 96 (9): 2786 -2795.
  • 8Corrias A, Mussa A. Thyroid nodules in pedi?atrics: which ones can be left alone, which ones must be investigated, when and how [ J]. J Clin Res Pediatr Endocrinol, 2013, 5 (Suppl 1): 57 - 69.
  • 9Fiore E, Vitti P. Serum TSH and risk of pa?pillary thyroid cancer in nodular thyroid disease [J]. J Clin Endocrinol Metab, 2012, 97 (4): 1134 -1145.
  • 10Tian L, Song Y, Xing M, et al. A novel role for thyroid - stimulating hormone: up?regulation of hepatic 3 - hydroxy - 3 - methyl - glutaryl - coenzyme A reductase expression through the cyclic adenosine monophosphatel protein kinase AI cyclic adenosine monophos?phate - responsive element binding protein pathway [J] . Hepatology, 2010, 52 (4): 1401 - 1409.

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