摘要
基于“虚气留滞”理论,探讨脑缺血再灌注的病理机制和临床治法,通过把握其中病机变化规律,为临床辨证施治提供理论研究。“虚气留滞”理论从中医整体观出发对脑缺血再灌注损伤进行病因病机剖析,“虚气”“留滞”互为因果,成为复合之邪,共同影响脑缺血再灌注损伤的发生与发展,其中“虚气”是发病的内在根据,“留滞”是发病的重要条件。“虚气”影响津血运行,导致“留滞”的产生;“留滞”是以内毒积聚为先,痰瘀阻络为损。“留滞”日久伤及正气,加重“虚气”的程度,是为复合病邪,临床治疗应“补虚”与“通滞”双管齐下,滋补肝肾、补益气血以补其虚,活血解毒、涤痰祛浊以通其滞。基于“虚气留滞”理论,执简驭繁,使脑缺血再灌注的病理机制简单明了,更可为临床治疗提供准绳,提高疗效。
To discuss the pathological mechanism and clinical treatment of cerebral ischemia-reperfusion based on theory of‘deficiency-qi stagantion’.To provide theoretical research for clinical syndrome differentiation and treatment,by grasping the change rule of pathogenesis.The theory of‘deficiency-q i stagnation’analyzes the etiology and pathogenesis of cerebral ischemia-reperfusion injury from the holistic view of traditional Chinese medicine.‘Deficiency-qi’and‘stagnation’interact as both cause and effect,and become a compound evil,which together affect the occurrence and development of cerebral ischemia-reperfusion injury.Among them,‘deficiency-qi’is the internal basis of the disease,‘retention’is an important condition of the disease.‘deficiency-qi’affects the operation of blood and fluid,and leads to‘stagnation’.‘Stagnation’is the accumulation of internal poison first,then phlegm and blood stasis block collateral for damage.‘Stagnation’for long time damage vital qi and aggravate the degree of‘deficiency-q i’,and it is the compound disease.In the clinic for this,the treatment should be both‘notifying deficiency’and‘dredging stagnation’,nourishing the liver and kidney,tonifying qi and blood to notifying its deficiency,promoting blood circulation,clearing phlegm and removing turbidity to dredging its stagnation.Based on the theory of‘deficiency-qi stagnation’,the pathological mechanism of cerebral ischemia-reperfusion is simple and clear,which can provide a criterion for clinical treatment and improve the curative effect.
作者
李为成
黎培爱
武志全
LI Weicheng;LI Pei’ai;WU Zhiquan(Sanya Central Hospital,The Third People’s Hospital of Hainan Province,Sanya 572000,China)
出处
《环球中医药》
CAS
2020年第10期1702-1706,共5页
Global Traditional Chinese Medicine
基金
三亚市医疗卫生科技创新项目(2017YW06)。
关键词
缺血再灌注损伤
虚气留滞
补虚通滞
病理机制
理论研究
Cerebral ischemia-reperfusion injury
Deficiency-qi stagnation
Notifying deficiency and dredging stagnation
Pathological mechanism
Theoty study
