摘要
皮质下梗死和白质脑病的常染色体显性遗传性脑动脉病(CADASIL)是一种中年发病的、非动脉硬化性、遗传性脑小动脉疾病,其典型临床表现为先兆性偏头痛、反复发作的脑卒中、多发性皮质下梗死、情感障碍、进行性血管性痴呆和认知功能损伤,但合并癫痫发作者较少见。本文主要分析1例易误诊为颅内感染的发热后出现持续性癫痫的CADASIL患者的临床特征、诊疗注意事项并进行文献复习,以增加临床医生对CADASIL诊断及鉴别的认识。
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy(CADASIL)is a middle-aged,non atherosclerotic,hereditary small cerebral artery disease,its typical clinical manifestations are migraine with aura,recurrent stroke,multiple subcortical infarcts,affective disorders,progressive vascular dementia,and cognitive impairment,while seizures is relatively rare.This article mainly analyzed the clinical features and precautions for diagnosis and treatment of a CADASIL patient with persistent epilepsy after fever who were easily misdiagnosed as intracranial infection,aiming to improve clinicians'understanding of the diagnosis and identification of CADASIL.
作者
陈艳
赵珊珊
CHEN Yan;ZHAO Shanshan(Department of Neurology,First Affiliated Hospital of China Medical University,Shenyang 110000,China)
出处
《实用心脑肺血管病杂志》
2020年第10期131-134,共4页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
