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米力农治疗充血性心力衰竭的效果 被引量:5

EFFECT OF TREATMENT OF CONGESTIVE HEART FAILURE WITH MILRINONE
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摘要 1目的 观察米力农治疗充血性心力衰竭的效果。2方法 采用国产米力农静脉点滴治疗充血性心力衰竭病人 2 2例 ,10 d后超声心动图测定其心功能 ,并与对照组进行比较。3结果 米力农治疗充血性心力衰竭总有效率达 86 .4% ,而对照组为 2 7.8% ,差异有显著性 (χ2 =14.15 8,P<0 .0 5 )。米力农治疗后每搏量、心排血量、射血分数、左室短轴缩短率均明显改善 (t=3.0 1~ 9.5 8,P<0 .0 5 ) ;治疗过程中未发现严重的副作用。4结论 米力农是治疗充血性心力衰竭的有效药物。 Objective To observe the effect of treatment of congestive heart failure with milrinone.\ Methods\ 22 cases of congestive heart failure were treated with Chinese made milrinone intravenously. The heart function was evaluated by ultrasonocardiography after ten days of treatment and the results compared with the control group.\ Results\ The total effective rate of milrinone was 86.4%, while the control group was 27.8%. The difference between two groups was significant( χ 2=14.158, P <0.05). After the treatment, SV,CO,EF,FS improved significantly ( t=3.01-9.58, P <0.05). No serious side effects were detected during treatment. \ Conclusion\ Milrinone is an effective medicine for the treatment of congestive heart failure. [
出处 《青岛大学医学院学报》 CAS 2000年第3期211-212,共2页 Acta Academiae Medicinae Qingdao Universitatis
关键词 米力农 充血性心力衰竭 磷酸二酯酶抑制剂 疗效 静脉注射 heart failure, congestive phosphodiesterase inhibitors therapeutics
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  • 1Young RA, Ward A. Milrinone: a preliminary review of its pharmacological properties and therapeutic use[J]. Drugs. 1988,36:158
  • 2Evans DB. Overview of cardiovascular physiologic and pharma cologic aspect of selective phosphodiesterase peak Ⅲ inhibitors [J]. Am J Cardicol, 1989, 63:9A
  • 3韩雅玲,祝善俊,鲁云敏,李隆贵,孟素荣,黄岚,刘凡光.国产氨利酮治疗风心病难治性心力衰竭的临床疗效研究[J].临床心血管病杂志,1990,6(1):1-4. 被引量:11
  • 4Krams R, McFalls E, Giessen WJ, et al. Dose intravenous milrinone have a direct effect on dlastolic function[J] Am Heart J,1991,121:1951
  • 5Packer M, Carver JR, Rodeheffer RJ, et al. Effect of oral milrinone on mortality in sever chronic heart failure[J]. N Engl J Med, 1991,325:1468

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