摘要
目的探讨大光斑低能量Q开关Nd:YAG激光联合超分子水杨酸治疗黄褐斑的临床有效性研究。方法募集在我科2016年8月-2020年3月收治的90例黄褐斑患者,随机分为三组:A组:30例,采用超分子水杨酸治疗,每两周治疗一次,共治疗5次为一个疗程;B组:30例,采用大光斑低能量Q开关、长脉宽1 064nm Nd:YAG激光治疗,1次/月,共5次;C组:30例,采用大光斑低能量Q开关、长脉宽1 064nm Nd:YAG激光治疗,1次/月,共5次,中间每次做完激光后两周采用超分子水杨酸穿插治疗一次,共治疗5次为一个疗程。结果 C组疗效明和MASI评分显优于A组和B组(P<0.05)。结论采用大光斑低能量Q开关、长脉宽1064nm Nd:YAG激光联合超分子水杨酸治疗黄褐斑患者,能明显提高患者的治疗效果,且不良反应轻微。
Objective To investigate the clinical effectiveness of large spot low-energy Q-switched Nd:YAG laser combined with supramolecular salicylic acid in the treatment of chloasma.Methods Ninety patients with chloasma admitted to our department from August 2016 to March 2020 were recruited and randomly divided into three groups:Group A:30 cases were treated with supramolecular salicylic acid and treated every two weeks.5 times of treatment is a course of treatment;group B:30 cases,using large spot,low energy Q-switch,long pulse width 1064nm Nd:YAG laser treatment,1 time/month,a total of 5 times;group C:30 cases,using large spot Lowenergy Q-switch,long pulse width 1064nm Nd:YAG laser treatment,1 time/month,5 times in total,supramolecular salicylic acid is used to intersect once every two weeks after the laser is done,and a total of 5 times is one treatment Course of treatment.Results The curative effect and MASI score of group C were significantly better than those of group A and group B(P<0.05).Conclusion The use of large spot,low energy Q-switch,long pulse width 1064nm Nd:YAG laser combined with supramolecular salicylic acid to treat patients with melasma can significantly improve the treatment effect of patients,and the adverse reactions are minor.
作者
谷晓广
刘永生
续言凤
高丹旭
邱晓圆
GU Xiao-guang;LIU Yong-sheng;XU Yan-feng;GAO Dan-xu;QIU Xiao-yuan(Department of Dermatology General Hospital of China Aviation,Beijing City,100012,China;Translational Medicine Research Institute of Chinese Academy of Sciences,Beijing City,100012,China)
出处
《中国医疗美容》
2020年第9期100-103,共4页
China Medical Cosmetology
