摘要
目的以大数据为基础探讨原发性骨质疏松症(primary osteoporosis,POP)的研究现状和研究热点。方法检索并获取Web of Science (Wo S)检索平台核心数据库中2009年1月1日至2019年7月29日有关POP研究的数据,并应用文献计量学方法进行分析,同时使用VOSviewer进行可视化呈现。结果共25 685篇文献纳入研究。中国总发文量位于第2位,被引频次排名第4,H指数排名第6。发文最多的机构是加州大学旧金山分校,发文最多的学者是Cooper教授,接收POP研究最多的期刊是Osteoporosis International;联合研究以在本国机构之间居多,跨国研究以美国最多。当前研究主题可分为4大类:基础研究、临床特点与诊断、外科治疗以及药物治疗。人群研究、骨小梁评分(trabecular bone score,TBS)、miRNA以及自噬在2018年以后出现频率较高。结论中国POP研究呈逐年增加趋势,但文章质量仍与西方发达国家存在差距。美国在POP研究领域依旧处于世界领先地位。各机构联合研究多倾向于在本国内合作。目前的研究主题呈现从疾病临床特点和诊断向治疗以及基础研究转变的趋势,基于人群大数据的临床研究、TBS、miRNA以及自噬有可能成为未来的研究热点。
Objective To reveal the trends and hotspots of primary osteoporosis(POP)research.Methods Original articles from January 1,2009 to July 29,2019 were collected from Web of Science Core Collection database.VOSviewer software was used to facilitate bibliometrics analysis and visualization of scientific productivity and emerging trends.Results A total of 25685 original articles were included in the study.China ranked the 2nd in total scientific output,the 4th in total citations,and the 6th in H index.The most productive institution was the University of California,San Francisco,while Professor Cooper was the most productive author.Osteoporosis International published the most articles about POP.Collaborations between institutions were more frequent among domestic agencies,while collaborations between countries were most in USA.The topics of POP researches can be divided into four categories:basic research,clinical characteristics and diagnosis,surgical treatment,and drug therapy.Population studies,trabecular bone score(TBS),microRNA,and autophagy were the most frequent topic words after 2018.Conclusions The annual scientific output on POP in China has been increasing rapidly,but there is still a gap between China and the western developed countries in terms of articles of high quality.USA still leads the world in the field of POP research.Institutions tend to collaborate in joint research with domestic agencies.Topics of POP researches have been developed from clinical features and diagnosis to treatment and basic research.Studies based on data from large populations,TBS,microRNA,and autophagy may be promising in the next few years.
作者
王宇鸣
高福强
邹海波
WANG Yu-ming;GAO Fu-qiang;ZOU Hai-bo(Department of Orthopedics,China-Japan Friendship Hospital,Beijing 100029,China)
出处
《中华骨质疏松和骨矿盐疾病杂志》
CSCD
北大核心
2020年第4期296-303,共8页
Chinese Journal Of Osteoporosis And Bone Mineral Research
