摘要
[目的]评价刷牙预防经口气管插管病人呼吸机相关性肺炎(VAP)的效果。[方法]计算机检索the Cochrane Library、JBI、PubMed、Web of Science、OVID、CINAHL、中国生物医学文献数据库(CBM)、中国期刊全文数据库(CNKI)、维普数据库(VIP)和万方数据库(Wanfang Data)中涉及刷牙对预防经口气管插管病人VAP效果的随机对照试验(RCT)和类实验性研究(CCT),检索时间为从建库至2019年3月31日。2名研究员完成文献筛选、数据提取和质量评价后,使用RevMan 5.3软件进行分析。[结果]共纳入6篇RCT,Meta分析结果显示:刷牙比传统的擦拭法口腔护理更能有效降低气管插管病人VAP发生率[RR=0.74,95%CI(0.58,0.93),P=0.01],但是刷牙并不能减少病人的机械通气时间[MD=-0.72,95%CI(-2.04,0.61),P=0.29]和ICU住院时间[MD=-1.50,95%CI(-3.37,0.36),P=0.11]。[结论]现有证据表明:刷牙能有效地降低经口气管插管病人VAP发生率。
Objective:To evaluate effect of toothbrushing on preventing ventilator-associated pneumonia(VAP)in patients with endotracheal intubation.Methods:Randomized controlled trials(RCTs)and quasi⁃experimental trials(CCTs)on effect of toothbrushing on preventing VAP in patients with endotracheal intubation,were retrieved from the Cochrane Library,JBI,PubMed,Web of Science,OVID,CINAHL,CBM,CNKI,VIP,Wanfang Data.The retrieval period was from establishment of databases to March 31,2019.The literature screening,data extraction and quality evaluation were completed by two researchers.And RevMan 5.3 software was used for analysis.Results:A total of 6 RCTs were included.Meta⁃analysis results showed that brushing teeth was more effective than traditional wiping oral care in reducing incidence of VAP in patients with endotracheal intubation[RR=0.74,95%CI(0.58,0.93),P=0.01].While brushing did not reduce patient's mechanical ventilation time[MD=-0.72,95%CI(-2.04,0.61),P=0.29]and length of ICU stay[MD=-1.50,95%CI(-3.37,0.36),P=0.11].Conclusions:Existing evidence shows that brushing teeth can effectively reduce incidence of VAP in patients with oral tracheal intubation.
作者
邵勤文
程红
景艳翠
韩飒飒
赵海平
SHAO Qinwen;CHENG Hong;JING Yancui;HAN Sasa;ZHAO Haiping(China Medical University,Liaoning 110122 China)
出处
《护理研究》
北大核心
2020年第18期3226-3232,共7页
Chinese Nursing Research
关键词
刷牙
气管插管
呼吸机相关性肺炎
口腔护理
META分析
toothbrushing
endotracheal intubation
ventilator⁃associated pneumonia
oral hygiene
Meta⁃analysis
