摘要
目的:探讨稳心颗粒结合单硝酸异山梨酯治疗急性心肌梗死的临床疗效。方法:选取2018年4月—2019年12月在我院治疗的94例急性心肌梗死患者,随机分为两组,各47例。对照组给予单硝酸异山梨酯治疗,观察组给予单硝酸异山梨酯+稳心颗粒治疗。治疗后,比较两组临床疗效、心率变异性指标、心功能。结果:治疗后,观察组治疗总有效率、全程NN间期的标准差(SDNN)、全程每5minNN间期均值的标准差(SDANN)、由迷走神经及交感神经共同介导的低频带(LF)、由迷走神经介导的高频带(HF)、左心室射血分数(LVEF)、左心室舒张末径(LVEDD)高于对照组,左心室高峰充盈率(LVPFR)低于对照组,差异具有统计学意义(P<0.05)。结论:稳心颗粒结合单硝酸异山梨酯治疗急性心肌梗死可提高临床疗效,改善心率变异性,改善心功能。
Objective:To explore the clinical effect of Wenxin Granule Combined with isosorbide mononitrate in the treatment of acute myocardial infarction.Methods:94 patients with AMI who were treated in our hospital from April 2018 to December 2019 were randomly divided into two groups,47 in each group.The control group was treated with isosorbide mononitrate,and the observation group was treated with isosorbide mononitrate + Wenxin granule.After treatment,the clinical effect,heart rate variability index and heart function of the two groups were compared.Results:After the treatment,the total effective rate,SDNN,SDANN,LF,HF,LVEF and LVPFR of the observation group were higher than those of the control group,and the LVEDD was lower than that of the control group,the difference was statistically significant (P<0.05).Conclusion:Wenxin Granule Combined with isosorbide mononitrate in the treatment of acute myocardial infarction can improve the clinical effect,heart rate variability and heart function.
作者
吴清华
WU Qing-hua(Department of Infection,Third People's Hospital,Shangqiu Henan 476000,China)
出处
《药品评价》
CAS
2020年第12期43-44,62,共3页
Drug Evaluation
关键词
急性心肌梗死
稳心颗粒
单硝酸异山梨酯
心率变异性指标
心功能
Acute Myocardial Infarction
Wenxin Granule
Isosorbide Mononitrate
Heart Rate Variability Index
Heart Function
