摘要
目的探究银翘散联合臭氧水疗治疗儿童寻常型银屑病血热风燥证的临床疗效。方法将40例符合此次临床观察的患者随机分组,对照组20例冲服消银颗粒,1袋(3.5 g)/次,日2次;治疗组20例温服汤剂150 mL/次,2次/d,联合臭氧水疗隔日1次,每次20 min。两组配合外用保湿品凡士林薄涂。其中治疗组因失联脱失1例,参与其他银屑病临床观察剔除1例,实际入组18例;对照组由于治疗初期皮损改善效果不佳脱失2例、患者依从性差剔除1例,实际入组17例。记录两组患者治疗前,治疗第2、4周的银屑病面积和严重程度指数(PASI)评分、瘙痒视觉模拟评分、中医症状评分,比较治疗效果。结果第4周,治疗组PASI评分、皮肤瘙痒评分均优于对照组(P<0.05);治疗组总有效率达77.77%,治疗组临床疗效好于对照组(P<0.05);治疗组皮肤干燥症状评分增加(P>0.05),两组小便黄、大便干症状均改善(P>0.05)。结论银翘散联合臭氧水疗对于儿童血热风燥型银屑病皮损有改善作用。
Objective To observe the clinical effect of Yinqiao San combined with ozone hydrotherapy on pediatric psoriasis vulgaris syndrome of blood heat and wind dryness. Methods 40 patients who met this clinical observation were randomly assigned,the control group,20 cases were treated with Xiaoyin Granules,bag(3.5 g)/time,2 times/day;In the treatment group,20 cases were treated with 150 mL decoction per time,2 times/day,combined ozone hydrotherapy once every other day,every 20 minutes. Two groups with external moisturizer vaseline thin coating. The treatment group,1 case was lost due to loss of contact,1 case was removed after participating in the clinical observation of other psoriasis,and 18 cases were actually included in the group. In the control group,2 cases were excluded due to poor improvement effect of initial skin lesions and 1 case was removed due to poor patient compliance,and 17 cases were actually included in the group. PASI scores,itch visual simulation scores and TCM symptom scores of the two groups of patients before and at the 2nd and 4th weeks of treatment were recorded to compare the treatment effect. Results At week 4,PASI score and itchy skin score in the treatment group were better than those in the control group(P<0.05). The apparent efficiency of the treatment group was 77.77%. The clinical effect of the treatment group was better than that of the control group(P<0.05). Skin dryness score increased in the treatment group(P>0.05),symptoms of yellow urine and dry stool improved in both groups(P<0.05).Conclusion Yinqiao San combined with ozone hydrotherapy can improve the skin lesions of pediatric with blood heat and wind dryness psoriasis.
作者
杨素清
王宇
王姗姗
YANG Suqing;WANG Yu;WANG Shanshan(First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,Heilongjiang,China;Heilongjiang University of Chinese Medicine,Harbin 150040,Heilongjiang,China)
出处
《辽宁中医药大学学报》
CAS
2020年第6期4-7,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家自然科学基金(81973846)
国家重点研发计划“中医药现代化研究”重点专项课题(2018YFC1705303)
黑龙江中医药大学科研基金(201806)。
关键词
银翘散
臭氧水疗
儿童银屑病
血热风燥
Yinqiao San
ozone hydrotherapy
pediatric psoriasis
blood heat and wind dryness
