摘要
为了对比4种梅毒血清学的实验室检查方法,对其准确性和临床价值进行分析。本文采用甲苯胺红不加热试验(TRUST)、酶联免疫吸附法(ELISA)、化学发光法、梅毒螺旋体明胶颗粒凝胶试验(TPPA)4种检测方法进行比较分析,得出每组试验间的差异,了解每组试验之间的关联性。结果显示,TRUST、ELISA、TPPA、化学发光法的特异性和敏感性的数据差异有统计学意义(P<0.05)。以TPPA为标准,化学发光法和ELISA的敏感性明显高于TRUST,而ELISA和化学发光法的特异性比较差异无统计学意义(P>0.05)。经过研究表明,ELISA与化学发光法可以成为TPPA的替代试验,值得在临床推广。
In order to compare the accuracy and clinical value of four syphilis serology laboratory tests,toluene red non-heating test(TRUST),enzyme-linked immunosorbent assay(ELISA),chemiluminescence method and treponema pallidum gelatin particle gel test(TPPA)are used for comparison and analysis in this paper,and each group is obtained differences between experiments to understand the correlation between each group of experiments.The results show that specificity and sensitivity of TRUST,ELISA,TPPA,and chemiluminescence are statistically significant(P<0.05).The sensitivity of chemiluminescence and ELISA is significantly higher than that of TRUST with TPPA as the standard.The difference between specific ELISA and chemiluminescence is not statistically significant(P>0.05).This study indicates that ELISA experiments and chemiluminescence methods have been shown to be surrogate experiments for TPPA and are worthy of clinical promotion.
作者
黄春明
HUANG Chunming(Jieyang Jiedong People's Hospital,Jieyang,Guangdong,522000,China)
出处
《质量安全与检验检测》
2020年第4期34-35,共2页
QUALITY SAFETY INSPECTION AND TESTING
