摘要
目的观察自拟通淋排石汤联合体外冲击波碎石术(ESWL)治疗输尿管结石的临床疗效。方法将2017年6月至2019年3月期间北京市大兴区中西医结合医院收治的164例输尿管结石患者,按就诊时间顺序随机分为对照组与研究组,各82例,对照组采用ESWL治疗,研究组自拟通淋排石汤联合ESWL治疗。观察并比较两组的临床疗效、临床症状、治疗前与治疗后7、14 d尿常规及并发症的发生情况。结果研究组的总有效率显著高于对照组(96.34%vs.86.58%,P=4.998,χ^2=0.025);治疗前两组症状积分差异无统计学意义(P>0.05),治疗后两组腹部绞痛、血尿、便意或尿意、恶心呕吐等临床症状积分均明显降低,且研究组的腹部绞痛、血尿、便意或尿意、恶心呕吐等症状积分均低于对照组(P<0.05);治疗前,两组患者尿WBC、RBC差异无统计学意义(P>0.05),治疗后7、14 d两组尿WBC、RBC明显低于治疗前,治疗后14 d两组尿WBC、RBC明显低于治疗后7 d,且研究组患者尿WBC、RBC均较对照组明显降低,差异有统计学意义(P<0.05);对照组患者治疗期间出现的并发症发生率(17.07%)明显高于研究组(6.09%)(χ^2=4.822,P=0.028)。结论自拟通淋排石汤联合ESWL治疗输尿管结石,可以增强两者协同作用,提高临床疗效,改善临床症状,加快尿WBC、RBC下降速度,促进结石排出,值得进一步临床推广。
Objective To investigate the clinical efficacy of self-made tonglin paishi decoction combined with extracorporeal shock wave lithotripsy(ESWL)in the treatment of ureteral calculi.Methods From June 2017 to March 2019,164 patients with ureteral calculi admitted to Daxing district hospital of traditional Chinese and western medicine of Beijing were selected and randomly divided into control group and study group according to the time of treatment,82 cases in each group.The control group was treated with extracorporeal shock wave lithotripsy.The study group was treated with tonglin paishi decoction combined with extracorporeal shock wave lithotripsy.The clinical efficacy,clinical symptoms,urine routine and complications of the two groups were observed and compared.Results The total effective rate of the study group after treatment was significantly higher than that of the control group(96.34%vs.86.58%,P=4.998,χ^2=0.025).The symptom scores between the two groups before treatment had no difference(P>0.05).After treatment,the scores of clinical symptoms such as abdominal colic,hematuria,urinary astringency,nausea and vomiting in both groups were significantly reduced.The scores of abdominal colic,hematuria,urination,nausea and vomiting in the study group were lower than those in the control group(P<0.05).The urinary WBC and RBC between the two groups had no difference(P>0.05).The urinary WBC and RBC in the two groups were significantly lower than those before treatment on the 7 th and 14 th day after treatment,and the urinary WBC and RBC in the two groups on the 14 th day after treatment were significantly lower than those on the 7 th day after treatment,which were decreased at the post-treatment 7 d and 14 d in the study group,with statistic difference between two groups(P<0.05).The incidence of complications during treatment was significantly higher in the control group than in the study group(17.07%vs.6.09%,χ^2=4.822,P=0.028).Conclusions Self-made tonglin paishi decoction combined with extracorporeal shock wave lithotripsy for ureteral calculi can effectively ameliorate the clinical symptoms,promote the decline of urinary WBC and RBC,as well as the stone discharge,which is worth further promotion.
作者
刘辉
宋健
乔庐东
吕双喜
Liu Hui;Song Jian;Qiao Ludong;Lyu Shuangxi(Department of Urology,Daxing District Hospital of Traditional Chinese and Western Medicine of Beijing,Beijing 102600,China;Department of Urology,Beijing Friendship Hospital,Beijing 100000,China;Department of Urology,Beijing Tongren Hospital,Beijing 100000,China)
出处
《国际泌尿系统杂志》
2020年第4期628-632,共5页
International Journal of Urology and Nephrology
基金
北京市大兴区中西医结合医院院级科研课题(DXZXY2017)。
关键词
输尿管结石
碎石术
自拟通淋排石汤
Ureteral Calculi
Lithotripsy
Self-made Tonglin Paishi Decoction
