摘要
目的:量化分析视频终端使用时长及屏幕蓝光照度对干眼相关眼表指标的影响。方法:前瞻性干预性试验研究。于2018年10─12月招募武汉爱尔眼科医院汉口医院非医学专业行政人员15名作为受试者,所有受试者依次进入无蓝光2 h、低蓝光2 h、高蓝光2 h、高蓝光4 h等环境进行试验,每次试验间隔2 d,以消除上次试验的影响。每次试验前后行快速干眼评估问卷调查(SPEED)、LipiView眼表干涉仪、Keratograph眼表综合分析仪及裂隙灯显微镜检查。采用一般线性回归分析、配对t检验、秩和检验等进行统计学分析。结果:低蓝光2 h、高蓝光2 h、高蓝光4 h较无蓝光2 h环境的SPEED评分分别增加2.07、2.13、4.20分(P=0.001,P=0.001,P<0.001);泪膜破裂时间(BUT)分别缩短1.83、0.27、1.99 s(P=0.028,P=0.746,P=0.017)。高蓝光2 h、高蓝光4 h较无蓝光2 h受试者的角膜荧光素染色评分分别增加0.47、0.43分(P=0.008,P=0.014);结膜荧光素染色评分分别增加0.33、0.30分(P=0.036,P=0.048)。各有蓝光环境间比较,高蓝光4 h较高蓝光2 h环境SPEED评分增加2.07分(P=0.002),较低蓝光2 h环境增加2.13分(P=0.003);高蓝光2 h较低蓝光2 h环境角膜荧光素染色评分增加0.4分(P=0.029)。其余指标差异均无统计学意义。结论:视频终端相关干眼与屏幕蓝光照度及使用时长有关,降低屏幕蓝光照度可减少角结膜上皮损伤。但即使降低屏幕蓝光照度,持续操作2 h仍可出现泪膜稳定性下降及眼部不适症状。
Objective:To analyze and quantify the changes in ocular surface parameters under conditions with different exposures to blue light from visual display terminals(VDTs).Methods:This was a prospective intervention study.Fifteen non-medical administrative staff members at Hankou Aier Eye Hospital were recruited from October to December 2018 and were sequentially tested under 4 test conditions with different exposures to blue light.Then all subjects were sequentially tested under conditions without blue light for 2 hours(non-2 h group),with a low dose of blue light for 2 hours(low-2 h group),with a high dose of blue light for 2 hours(high-2 h group)and with a high dose of blue light for 4 hours(high-4 h group).Each test was conducted over an interval of 2 days to eliminate the effects of the previous test.Symptoms of subjects were evaluated by the Standard patient evaluation of eye dryness(SPEED)questionnaire.The other examinations were as follows:Lipi view ocular surface interferometer,OCULUS Keratograph 5M and slit-lamp microscopy.All examinations were repeated before and after each test.A general linear regression analysis,paired t test and rank sum test were used for statistical analysis.Results:With the non-2 h group as the control,the SPEED scores of the low-2 h group,high-2 h group and high-4 h group increased 2.07 points,2.13 points and 4.20 points,respectively(P=0.001,P=0.001,P<0.001).The tear film break-up time decreased by 1.83 s,0.27 s and 1.99 s,respectively(P=0.028,P=0.746,P=0.017).Compared to the non-2 h control group,the cornea and conjunctiva fluorescence staining scores in the high-4 h group and high-2 h group increased by 0.47 points,0.43 points and 0.33 points,0.30 points,respectively(P=0.008,P=0.014;P=0.036,P=0.048).The SPEED scores in the high-4 h group increased by 2.07 points compared to the high-2 h group(P=0.002),and by 2.13 points in the high-4 h group compared to the low-2 h group(P=0.003).There was a 0.4 point increase in corneal staining score in the high-2 h group compared to the low-2 h group(P=0.029).There were no statistically significant differences among other parameters.Conclusions:The illuminance of blue light from VDTs and the operating time of VDTs affects the occurrence and development of dry eye disease.Reducing the dose of blue light from VDT screens can decrease the damage to the epithelial cells of the cornea and conjunctiva.Even with a low dose of blue light exposure,the group that was exposed to the VDT for 2 hours show a decrease in tear film stability and an increase in symptoms.
作者
吴小曼
谌丹
戚梦莹
曾庆延
Wu Xiaoman;Shen Dan;Qi Mengying;Zeng Qingyan(Aier School of Ophthalmology,Central South University,Changsha 410015,China;Hankou Aier Eye Hospital,Wuhan 430024,China)
出处
《中华眼视光学与视觉科学杂志》
CAS
CSCD
2020年第6期441-447,共7页
Chinese Journal Of Optometry Ophthalmology And Visual Science
基金
武汉市卫生和计划生育委员会科研项目(WX17D46,WX17A13)
爱尔眼科医院集团科研基金(AFQ1704D1)。
关键词
视频终端
蓝光
干眼
泪膜
visual display terminal
blue light
dry eye
tear film
