摘要
目的探讨婴幼儿血清25-羟维生素D3影响因素分析及药物联合行为干预的效果。方法选择肇庆市第一人民医院2016年3月—2017年3月入院治疗的婴幼儿50例,50例均为维生素D缺乏症患儿,使用随机数字表法将患儿分为对照组以及研究组,各25例。对照组接受行为干预,研究组接受药物联合行为干预,对比两组患儿的疗效差异。结果两组患儿治疗前的血清25-羟维生素D3(25-(OH)D3)、血钙、血磷、骨钙素(osteocalcin,OC)、骨源性碱性磷酸酶(bone-derived alkaline phosphatase,BALP)水平对比,研究组与对照组无显著差异,无统计学意义(P>0.05);在接受不同的干预后,研究组与对照组的各项生理指标均有所改善,研究组25-(OH)D3、血钙、血磷、BGP低于对照组,研究组BALP水平高于对照组,P<0.05差异具有统计学意义。结论婴幼儿的喂养方式以及胃肠道功能是影响血清25-羟维生素D3重要因素,在给予患儿药物联合行为干预后,能够改善婴幼儿的胃肠功能、促进婴幼儿健康生长发育。
Objective To investigate the influencing factors of serum 25-hydroxyvitamin D3 in infants and the effect of drug combined behavioral intervention.Methods 50 infants admitted to two hospitals in Zhaoqing from March 2016 to March 2017 were selected,50 of which were children with vitamin D deficiency.The children were divided into control group and study group with 25 cases in each group by random number table.The control group received behavioral intervention,while the research group received drug combined behavioral intervention.The therapeutic effects of the two groups were compared.Results The levels of serum 25-hydroxyvitamin D3(25-(OH)D3),blood calcium,blood phosphorus,osteocalcin(OC),bone-derived alkaline phosphatase(BALP)before treatment in the two groups were compared.There was no significant difference between the study group and the control group,and there was no statistical significance(P>0.05).After receiving different interventions,the physiological indexes of the study group and the control group were improved.the levels of 25-(OH)D3,blood calcium,blood phosphorus and BGP in the study group were lower than those in the control group,and the level of BALP in the study group was higher than that in the control group(P<0.05)with statistical significance.Conclusion Feeding mode and gastrointestinal function of infants are important factors that affect serum 25-hydroxyvitamin D3.After giving children drugs combined with behavioral intervention,it can improve gastrointestinal function of infants and promote healthy growth and development of infants.
作者
陈莉莉
区肇真
夏伟桃
CHEN Lili;OU Zhaozhen;XIA Weitao(Department of Neonatology,The First People's Hospital of Zhaoqing,Zhaoqing Guangdong 526060,China;Department of Pediatrics,The First People's Hospital of Zhaoqing,Zhaoqing Guangdong 526060,China;Department of Child Healthcare,The First People's Hospital of Zhaoqing,Zhaoqing Guangdong 526060,China)
出处
《中国卫生标准管理》
2020年第14期98-100,共3页
China Health Standard Management
关键词
婴幼儿
血清25-羟维生素D3
影响因素
药物干预
行为干预
临床效果
infants and young children
serum 25-hydroxyvitamin D3
influencing factors
drug intervention
behavioral intervention
clinical effect
