摘要
目的:探究橡皮生肌膏治疗慢性难愈性皮肤溃疡的效果.方法:选取2018年1月-2019年1月本院收治的62例慢性难愈性皮肤溃疡患者为研究对象,根据采用的不同的治疗方案将其分为对照组与研究组,每组31例,对照组采用洗必泰治疗,而研究组采用橡皮生肌膏治疗,观察比较两组患者的临床效果、治疗前后Ⅰ型胶原/Ⅲ型胶原比值以及创面分泌物情况.结果:治疗后,研究组的总有效率明显高于对照组;同时研究组的Ⅰ型胶原/Ⅲ型胶原比值高于对照组;且研究组的成纤维细胞生长因子-2(FibrobLast Growth Factor-2,FGF-2)、血管内皮生长因子(Vascular Endothelial Growth Factor,VEGF)及纤维连接蛋白(Fiber Connection,Fn)的水平明显高于对照组(P<0.05).结论:采用橡皮生肌膏治疗慢性难愈性皮肤溃疡能有效提升临床效果,并促进Ⅰ型胶原合成,加快创面愈合.
Objective:To explore the effect of the Xiangpi Shengji ointment(橡皮生肌膏)on chronic refractory skin ulcer.Methods:62 patients divided into a control group and a research group,31 cases in each group The control group was treated with chlorhexidine and the research group was treated with the Xiangpi Shengji ointment.Results:After treatment,the total efficiency in the study group was significantly higher than the control group.The ratio of typeⅠcollagen/typeⅢcollagen in the study group was higher than the control group,and the fibroblast growth factor-2,VEGF,and Fiber Connection levels were significantly higher than the control group(P<0.05).Conclusion:The Xiangpi Shengji ointment can effectively improve the clinical effect,promote the synthesis of typeⅠcollagen,and accelerate the wound healing.
出处
《中医临床研究》
2020年第20期132-133,共2页
Clinical Journal Of Chinese Medicine
关键词
慢性难愈性皮肤溃疡
橡皮生肌膏
临床效果
Chronic refractory skin ulcers
The Xiangpi Shengji ointment
Clinical effects
