摘要
目的探讨黄斑变性雷珠单抗治疗后短期眼压升高的影响因素。方法选取2017年10月至2019年10月在我院接受雷珠单抗治疗的492例黄斑变性患者为研究对象,根据治疗后是否出现短期眼压升高(注射后10 min眼压升高≥10 mmHg)将其分为升高组(91例,91眼)和未升高组(401例,401眼),比较两组患者相关资料,分析导致黄斑变性雷珠单抗治疗后短期眼压升高的相关因素。结果单因素分析显示,年龄、注射前眼压、注射次数是黄斑变性雷珠单抗治疗后短期眼压升高的相关因素(P<0.05)。多因素logistic回归分析显示,年龄、注射前眼压、注射次数是黄斑变性雷珠单抗治疗后短期眼压升高的独立危险因素(P<0.05)。结论年龄、注射前眼压及注射次数是黄斑变性雷珠单抗治疗后短期眼压升高的危险因素,故对年龄偏高、注射前眼压较高和注射次数较多的患者护理人员应予以特殊关注,并采取相应预防措施。
Objective To explore the influencing factors of short-term intraocular pressure increasing after treatment with ranibizumab in macular degeneration.Methods To select 492 cases of patients with macular degeneration who were treated with ranibizumab in our hospital from October 2017 to October 2019 as the study objects.According to whether there was a short-term increasing in intraocular pressure after treatment(increased intraocular pressure at 10 minutes after injection≥10 mmHg),they were divided into a increasing group(91 cases,91 eyes)and non-increasing group(401 cases,401 eyes).The relevant data of the two groups were compared,and the related factors leading to the short-term increasing in intraocular pressure after ranibizumab treatment in macular degeneration were analyzed.Results Univariate analysis showed that the age,intraocular pressure before injection and the number of injections were the related factors for the short-term increasing in intraocular pressure after ranibizumab treatment in macular degeneration(P<0.05).Multivariate logistic regression analysis showed that the the age,intraocular pressure before injection and the number of injections were the independent risk factors for the short-term increasing in intraocular pressure after ranibizumab treatment in macular degeneration(P<0.05).Conclusion The age,intraocular pressure before injection and the number of injections were the risk factors for the short-term increasing in intraocular pressure after ranibizumab treatment in macular degeneration.So,the nursing staff of patients with high age,high intraocular pressure before injection and frequent injections should be paid special attention and take corresponding preventive measures should be taken.
出处
《护理实践与研究》
2020年第14期88-90,共3页
Nursing Practice and Research
关键词
黄斑变性
雷珠单抗治疗
短期眼压升高
影响因素
Macular degeneration
Ranibizumab treatment
Short-term intraocular pressure increasing
Influencing factors
