摘要
目的调查合肥地区ICU后综合征(PICS)发生现状以及影响因素分析。方法选取合肥市某三级甲等医院2019年8月到2020年1月在ICU病房进行住院治疗后转出并符合纳入排除标准的危重患者为研究对象。收集所有患者的一般资料、治疗相关参数、护理记录等临床基数资料,同时对患者行PICS诊断,并根据诊断结果分为未发生组和发生组。统计合肥地区的ICU后综合征的发生率,同时单因素分析各临床基数资料对PICS发生影响并行多因素Logistic回归分析PICS发生独立危险因素。结果本研究实际有效样本量为280例,有191例发生PICS,PICS发生率为68.21%。单因素分析显示,年龄、性别、生活习惯、是否锻炼、ICU住院时长、机械通气时长、无创通气时长、约束时长、镇静药使用量(右美托咪定、丙泊酚、咪达唑仑)均是PICS发生影响因素(P<0.05),同时多因素回归分析显示,年龄、性别、生活习惯、是否锻炼、无创通气时长、约束时长、镇静药使用量(丙泊酚、咪达唑仑)是PICS发病独立危险因素(P<0.05)。结论该三甲医院PICS发生率较高,患者年龄、性别及治疗方法等均可影响PICS发生。其中年龄、性别、生活习惯、锻炼情况、无创通气时间、丙泊酚使用量是发生ICU后综合征的独立危险因素。
Objective To investigate the current status of post intensive care syndrome(PICS)and analysis of influencing factors.Methods Critically ill patients who were transferred from an ICU ward in August 2019 to January 2020 to a Critical ICU ward and met the exclusion criteria were selected as the research objects.Collecting clinical basal data such as general information,treatment-related parameters,and nursing records of all patients.PICS diagnosis was performed on patients at the same time and according to the diagnosis results,they were divided into PICS non-occurrence group and PICS occurrence group.The influence of each clinical base data on the occurrence of PICS was analyzed by univariate analysis.Multivariate logistic regression analysis was used to analyze the independent risk factors of PICS.Results The effective sample size for this study was 280 cases,with 191 cases of PICS,and the incidence rate of PICS was 68.21%.Univariate analysis showed age,gender,lifestyle,exercise,ICU length of stay,duration of mechanical ventilation,duration of non-invasive ventilation,duration of restraint,and sedative use(dexmedetomidine,propofol,midazolam),all were the influencing factors of PICS(P<0.05).Multivariate regression analysis showed that age,sex,lifestyle,exercise,non-invasive ventilation duration,restraint duration,and sedative use(propofol,midazolam)were independent risk factors for PICS(P<0.05).Conclusion The incidence of PICS is higher in Zunyi,Guizhou.Patients’age,gender,and treatment methods can affect the occurrence of PICS.Among them,age,gender,lifestyle,exercise,non-invasive ventilation time,propofol use,and midazolam use are independent risk factors for post intensive care syndrome.
作者
王颖
江智霞
傅小云
陈芳
何曼曼
陈德友
张芳
张习莹
Wang Ying;Jiang Zhixia;Fu Xiaoyun;Chen Fang;He Manman;Chen Deyou;Zhang Fang;Zhang Xiying(Department of Nursing,Affiliated Hospital of Zunyi Medical University,Zunyi Guizhou 563099,China;Department of Critical Care Medicine,Affiliated Hospital of Zunyi Medical University,Zunyi Guizhou 563099,China)
出处
《合肥医科大学学报》
2020年第3期353-357,共5页
Journal of Zunyi Medical University
基金
2017年度学术新苗培养及创新探索专项资助项目(NO:黔科合平台人才[2017]5733-073)。
关键词
危重症
ICU后综合征
发生现状
影响因素
critical care
post intensive care syndrome
occurrence status
influencing factor
