摘要
目的研究食管癌放疗前后血清肿瘤标志物的变化情况。方法以2017年10月—2019年9月本院接诊的食管癌病患43例为试验组,并对其施以放疗。选择本院同期接诊的健康体检者43名为对照。检测试验组放疗前后与对照组的血清肿瘤标志物水平,包括SCC、CYFRA21-1和CEA,并作对比。结果试验组放疗前血清CYFRA21-1、CEA和SCC水平比对照组高,放疗后血清CYFRA21-1、CEA和SCC水平比放疗前低(P <0.05)。试验组治疗有效率为62.79%。结论通过对血清肿瘤标志物SCC、CYFRA21-1和CEA水平进行检测,能够为食管癌病患病情的诊断及预后评估提供重要指导。
Objective To study the changes of serum tumor markers before and after radiotherapy for esophageal cancer. Methods From October 2017 to September 2019, 43 patients with esophageal cancer in our hospital were selected as the experimental group and treated with radiotherapy. 43 healthy people who received physical examination at the same time were selected as the control group. The levels of serum tumor markers, including SCC, CYFRA21-1 and CEA, were measured before and after radiotherapy in the experimental group and in the control group. Results The levels of CYFRA21-1, CEA and SCC in the experimental group before radiotherapy were higher than those in the control group, and the levels of CYFRA21-1, CEA and SCC after radiotherapy were lower than those before radiotherapy(P<0.05). The effective rate of the experimental group was 62.79%. Conclusion The detection of serum tumor markers SCC, CYFRA21-1 and CEA can provide important guidance for the diagnosis and prognosis of esophageal cancer patients.
作者
王超
WANG Chao(Department of Oncology,Xianning Central Hospital(The First Affiliated Hospital of Hubei University of Science and Technology),Xianning Hubei 437100,China)
出处
《中国继续医学教育》
2020年第21期114-116,共3页
China Continuing Medical Education
关键词
肿瘤标志物
食管癌
预后评估
放疗
水平变化
诊断
tumor markers
esophageal cancer
prognosis evaluation
radiotherapy
level change
diagnosis
