摘要
子宫内膜癌(EC)是我国妇科常见的3大恶性肿瘤之一。目前,EC发病率呈逐年上升趋势。EC在发病早期是一种相对惰性和可治愈的疾病,而至疾病晚期或复发时,则侵袭性较高。对EC患者准确地进行术前评估,对于制定个体化治疗方案至关重要。MRI作为EC最准确的医学影像学检查方法,可以在术前确定该病患者的国际妇产科联盟(FIGO)临床分期及进行预后评估。目前,除常规MRI检查外,MRI动态增强灌注成像(DCE-MRI)、弥散张量成像(DTI)和体素内不相干运动成像(IVIM)等新技术,在EC患者的术前及预后评估中的应用,已经成为本领域研究热点。笔者拟就EC患者的MRI表现与其FIGO临床分期的关系,EC患者诊治中的MRI新技术,以及MRI对于保留生育功能EC患者的预测价值的研究、应用现状等进行阐述。
Endometrial carcinoma(EC)is one of three most common gynecological malignant tumors in China,and its incidence is with ascending tendency in recent years.EC is a relatively inert and curable disease in early stage,while it is highly aggressive in late stage or recurrence.The accurate preoperative evaluation is an important examination strategy for treatment of EC.MRI as the most accurate imaging examination method for EC can distinguish its clinical stage of International Federation of Gynecology and Obstetrics(FIGO)and evaluate its prognosis.In recent years,except for routine MRI,the application of dynamic contrast enhanced MR imaging(DCE-MRI),diffusion tensor imaging(DTI),intravoxel incoherent motion(IVIM)and other new imaging methods in preoperative and prognostic evaluation of EC have become a hotspot in this field.This paper focuses on the latest research status of relationship between MRI findings of patients with EC and its clinical stage of FIGO,new MRI technologies in diagnosis and treatment of EC patients,and predictive values of MRI in EC patients with fertility preservation.
作者
叶芷君
宁刚
李学胜
白万晶
Ye Zhijun;Ning Gang;Li Xuesheng;Bai Wanjing(Department of Radiology,Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University),Ministry of Education,West China Second University Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China)
出处
《中华妇幼临床医学杂志(电子版)》
CAS
2020年第3期257-265,共9页
Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
基金
国家重点研发计划项目(2017YFC0109004)。
关键词
子宫内膜肿瘤
子宫肌层
动态增强MRI
磁共振成像
弥散
体素内不相干运动成像
肿瘤浸润
生育力
女(雌)性
Endometrial neoplasms
Myometrium
Dynamic contrast enhanced MR imaging
Diffusion magnetic resonance imaging
Intravoxel incoherent motion
Tumor infiltration
Fertility
Female