颅脑外伤后进展性出血患者凝血指标水平及与预后的关系被引量：4

The Relationship Between Coagulation Index and Prognosis in Patients with Progressive Hemorrhage after Craniocerebral Trauma

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摘要目的探究颅脑外伤后进展性出血患者凝血指标水平及与预后的关系。方法以122例颅脑外伤后进展性出血患者为对象,检测患者凝血指标,并分析其与患者病情及预后的关系。结果三组PT、D-D、PLT水平比较有差异,其中重型组高于轻型组与中型组,中型组高于轻型组(P<0.05)。PT、D-D、PLT与GCS评分呈负相关(P<0.05),aPTT与GCS评分无相关性(P>0.05)。对122例颅脑外伤后进展性出血患者进行3个月的随访观察,结果显示38例(31.15%)患者预后不良。Logistic多因素回归分析显示严重程度(OR=4.382,95%CI:1.638~14.072,P<0.001)、D-D(OR=3.175,95%CI:1.329~10.164,P<0.001)、PLT(OR=3.864,95%CI:1.407~11.201,P<0.001)为颅脑外伤后进展性出血患者预后不良的独立危险因素。结论凝血功能与颅脑外伤后进展性出血患者的病情密切相关,并且PLT、D-D是颅脑损伤后进展性出血患者预后不良的独立危险因素。

作者郭紫康权天龙 GUO Zi-kang;QUAN Tian-long(Department of Neurosurgery,The Central Hospital of Ankang,Ankang 725000,China)

机构地区安康市中心医院神经外科

出处《血栓与止血学》 2020年第4期641-643,共3页 Chinese Journal of Thrombosis and Hemostasis

关键词颅脑损伤进展性出血凝血指标

分类号 R651.1 [医药卫生—外科学]

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参考文献6

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