摘要
目的分析能谱CT定量分析在非小细胞肺癌(NSCLC)术前诊断中的临床价值。方法搜集河南省中医院经病理证实的120例NSCLC患者临床资料,分析其能谱CT定量参数[平扫能谱曲线40~65keV斜率(K40~65keV)、有效原子序数(EffZ)、钙(水)浓度及动脉期K40~65keV、碘(水)浓度、水(碘)浓度]与病理参数的关系,分析能谱CT定量参数对NSCLC评估价值。结果腺癌患者平扫能谱曲线K40~65keV、EffZ、钙(水)浓度及动脉期能谱曲线K40~65keV、碘(水)浓度高于鳞癌,水(碘)浓度低于鳞癌(P<0.05);低分化者平扫能谱曲线K40~65keV、EffZ及动脉期能谱曲线K40~65keV、碘(水)浓度低于中高分化者,而动脉期水(碘)浓度高于中高分化者(P<0.05);TNM分期Ⅱ~Ⅲ期患者平扫能谱曲线K40~65keV、EffZ及动脉期能谱曲线K40~65keV、碘(水)浓度低于Ⅰ期患者(P<0.05);淋巴结转移患者平扫能谱曲线K40~65keV、EffZ及动脉期能谱曲线K40~65keV、碘(水)浓度较无淋巴结转移者低(P<0.05);能谱CT定量参数中平扫K40~65keV的AUC最高(0.897)。结论 NSCLC患者术前进行能谱CT检查有利于判断其病理类型、分化程度、TNM分期及有无淋巴结转移,尤其是平扫K40~65keV、EffZ、碘(水)浓度诊断效果较好。
Objective To analyze the clinical value of energy spectrum CT quantitative analysis in the preoperative diagnosis of non-small cell lung cancer (NSCLC).Methods The clinical data of 120 patients with NSCLC confirmed by pathology were collected.The relationship between energy spectrum CT quantitative parameters [plain scan energy spectrum curve 40~65keV slope (K40~65keV),effective atomic number (EffZ),calcium (water) concentration,arterial phase K40~65keV,iodine (water) concentration,water (iodine) concentration] and pathological parameters was analyzed.The evaluation value of energy spectrum CT quantitative parameters for NSCLC was also analyzed.Results The plain scan energy spectrum curve K40~65keV,EffZ,calcium (water) concentration,arterial phase energy spectrum curve K40~65keV and iodine (water) concentration in patients with adenocarcinoma were higher than those with squamous cell carcinoma,and water (iodine) concentration was lower than those with squamous cell carcinoma (P<0.05).The plain scan energy spectrum curve K40~65keV,EffZ,arterial phase energy spectrum curve K40~65keV and iodine (water) concentration in patients with low differentiation were lower than those with moderate and high differentiation,while the arterial phase water (iodine) concentration was higher than those with moderate and high differentiation (P<0.05).The plain scan energy spectrum curve K40~65keV,EffZ,arterial phase energy spectrum curve K40~65keV and iodine (water) concentration in patients with TNM stage Ⅱ~Ⅲ were lower than those with stage Ⅰ(P<0.05).The plain scan energy spectrum curve K40~65keV,EffZ,arterial phase energy spectrum curve K40~65keV and iodine (water) concentration in patients with lymph node metastasis were lower than those without (P<0.05).Among the CT quantitative parameters,the AUC of plain scan K40~65keV was the largest (0.897).Conclusion Preoperative energy spectrum CT scan of patients with NSCLC can help with the judgement of pathological type,differentiation degree,TNM stage and lymph node metastasis.Besides,the diagnosis of K40~65keV,EffZ and iodine (water) concentration is relatively better.
作者
史志勇
SHI Zhi-yong(Department of Nuclear Medicine,Henan Traditional Chinese Medicine Hospital,Zhengzhou 450000,Henan Province,China)
出处
《中国CT和MRI杂志》
2020年第9期76-78,F0003,共4页
Chinese Journal of CT and MRI
关键词
能谱CT
定量
非小细胞肺癌
诊断
Energy Spectrum CT
Quantification
Non-small Cell Lung Cancer
Diagnosis
