摘要
目的分析定量CT测量与慢性阻塞性肺疾病(COPD)患者肺功能的相关性。方法收集2017年1月至2018年1月收治的90例COPD患者的临床资料,所有患者入院后均接受定量CT检查,分析COPD患者定量CT参数与肺功能的关系。结果不同分级COPD患者LAA%、WA%、TDR比较差异有统计学意义(P<0.05),随COPD等级的上升,LAA%、WA%、TDR增加(P<0.05);不同分级患者肺功能指标FEV1%、FEV1/FVC、DLCO%、RV/TLC比较差异均有统计学意义(P<0.05),随分级的提升,患者FEV1%、FEV1/FVC、DLCO%降低,RV/TLC上升(P<0.05);LAA%、WA%、TDR与FEV%、FEV/FVC、DLCO均呈负相关(P<0.05),与RV/TLC呈正相关(P<0.05)。结论 CT定量参数LAA%、WA%、TDR与肺功能指标FEV%、FEV/FVC、DLCO呈负相关,与RV/TLC呈正相关,均可作为评估COPD患者肺功能损伤程度的依据。
Objective To analyze the correlation between quantitative CT measurement and pulmonary function in patients with chronic obstructive pulmonary disease (COPD).Methods The clinical data of 90 patients with COPD admitted from January 2017 to January 2018 were collected.All patients underwent quantitative CT examination after admission.The relationship between quantitative CT parameters and pulmonary function in patients with COPD was analyzed.Results There were significant differences in LAA%,WA% and TDR among patients with COPD in different grades (P<0.05).LAA%,WA% and TDR increased with the increase of COPD level (P<0.05).There were significant differences in pulmonary function indexes such as FEV1%,FEV1/FVC,DLCO% and RV/TLC among patients with different grades (P<0.05).With the increase of grade,the FEV1%,FEV1/FVC and DLCO% decreased,while RV/TLC increased (P<0.05).LAA%,WA% and TDR were negatively correlated with FEV%,FEV/FVC and DLCO (P<0.05).while positively correlated with RV/TLC (P<0.05).Conclusion The quantitative CT parameters such as LAA,WA% and TDR are negatively correlated with FEV%,FEV/FVC and DLCO,while positively correlated with RV/TLC.Which could be used as basis for assessing the degree of pulmonary function injury in patients with COPD.
作者
姜伟强
高会艳
JIANG Wei-qiang;GAO Hui-yan(Department of Radiology,Xuchang Central Hospital,Xuchang 461001,Henan Province,China)
出处
《中国CT和MRI杂志》
2020年第9期73-75,85,共4页
Chinese Journal of CT and MRI
关键词
慢性阻塞性肺疾病
定量CT
肺功能
肺容积
Chronic Obstructive Pulmonary Disease
Quantitative CT
Pulmonary Function
Lung Volume
