摘要
目的:探讨前房注射头孢呋辛对白内障术后眼内炎的预防效果。方法:选取2017年12月-2019年12月于笔者所在医院行超声乳化白内障摘除术患者300例,随机分为研究组与对照组各150例,对照组术毕后前房未予注入药物,研究组术毕后于前房注入头孢呋辛。比较两组术前与术后3 d血清肿瘤坏死因子-α(TNF-α)、高敏C反应蛋白(hs-CRP)与白细胞计数(WBC)水平,比较术后疼痛状况及术后7 d内眼内炎发生情况。结果:术后3 d研究组TNF-α、hs-CRP与WBC水平均低于对照组(P<0.05);观察组术后疼痛状况优于对照组(P<0.05);术后7 d内研究组眼内炎发生率低于对照组(P<0.05)。结论:白内障术中予前房注射头孢呋辛可降低患者炎症因子水平,有效预防术后眼内炎的发生,减轻术后疼痛。
Objective:To explore the preventive effect of intracameral injection of cefuroxime on endophthalmitis after cataract surgery.Method:From December 2017 to December 2019,300 patients who underwent phacoemulsification in the authors’hospital were randomly divided into the study group and the control group,150 cases in each group.After surgery,the control group was not given intracameral injection of drugs,while study group was given intracameral injection of Cefuroxime.The levels of serum tumor necrosis factor-α(TNF-α),high-sensitivity C-reactive protein(hs-CRP)and white blood cell count(WBC)before surgery and at 3 d after surgery,postoperative pain and the occurrence of endophthalmitis within 7 d after surgery were compared between the two groups.Result:At 3 d after surgery,levels of TNF-α,hs-CRP and WBC in the study group were lower than those in the control group(P<0.05).The postoperative pain in the study group was milder than that in the control group(P<0.05).Within 7 d after surgery,incidence of endophthalmitis in the study group was lower than that in the control group(P<0.05).Conclusion:Intracameral injection of Cefuroxime during cataract surgery can reduce the levels of inflammatory factors in patients,effectively prevent the occurrence of postoperative endophthalmitis and alleviate postoperative pain.
作者
杨莎
何健强
陈博文
YANG Sha;HE Jianqiang;CHEN Bowen(Taishan People’s Hospital,Taishan 529200,China;不详)
出处
《中外医学研究》
2020年第20期138-140,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
头孢呋辛
白内障手术
眼内炎
炎症因子
Cefuroxime
Cataract surgery
Endophthalmitis
Inflammatory factor
