摘要
目的:了解导致老年维持性血液透析(maintain hemodialysis,MHD)患者发生心血管疾病的影响因素。方法:选择2016年1月-2019年11月在皖南医学院第二附属医院进行维持性血液透析治疗的老年慢性肾衰竭患者74例。按照是否发生心血管疾病(cardiovascular disease,CVD)分为CVD组(n=36),N-CVD组(n=38)。收集一般病史资料、实验室数据、彩色超声心动图指标。采用单因素、多因素Logistic回归分析方法进行统计学分析。结果:两组透析方式、间期体重增长、血红蛋白、白蛋白、左房内径、左室射血分数、舒张期室间隔厚度、舒张期左室后壁厚度比较差异有统计学意义(P<0.05);在单因素Logistic分析结果中,血红蛋白、白蛋白是发生CVD的保护性因素,而间期体重增加、左房内径、舒张期室间隔、舒张期左室后壁厚度是危险因素(P<0.05);多因素Logistic分析结果中,左房内径、间期体重增加是老年MHD患者并发CVD的独立危险因素(P<0.05)。结论:左房内径增大、间期体重增加对老年MHD患者发生CVD具有重要的影响。
Objective:To investigate the related factors of cardiovascular disease(CVD)in elderly patients receiving long-term hemodialysis(HD).Method:A total of 74 elderly patients who received HD therapy in the Second Affiliated Hospital of Wannan Medical College from January 2016 to November 2019 were selected.The patients were divided into two groups by cardiovascular disease(CVD):CVD group(n=36)and N-CVD group(n=38).General medical history,laboratory data and color echocardiography were collected.Single factor and multi factor Logistic regression analysis was used for statistical analysis.Result:There were significant differences in dialysismode,IDWG,hemoglobin,albumin,LA,IVSd,LVPWd,LVEF between CVD group and N-CVD group(P<0.05).The univariate Logistic regression analysis showed that hemoglobin and albumin were protective factors for CVD,while weight gain,left atrial diameter,diastolic interventricular septum and diastolic posterior wall thickness were risk factors(P<0.05).Multivariate Logistic regression analysis revealed that LA,IDWG were independent risk factor of CVD in HD patients(P<0.05).Conclusion:LA,IDWG are independent risk factor of CVD in patients receiving long-term hemodialysis.
作者
何禾
杨沿浪
HE He;YANG Yanlang(The First Affiliated Hospital of Wannan Medical College,Wuhu 241000,China;不详)
出处
《中外医学研究》
2020年第19期43-46,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
