摘要
目的总结新型冠状病毒肺炎(COVID-19)患者治愈出院的临床特点,提高其救治水平。方法对44例COVID-19患者的临床症状、实验室检查、影像学特征、治疗方法及预后进行分析。结果COVID-19患者主要症状为发热、乏力、咳嗽、咳痰、胸闷气短、喘息、食欲差等,治疗后咳嗽、活动后胸闷气短、乏力症状恢复慢。COVID-19患者入院时10例(22.73%)白细胞计数、24例(54.55%)淋巴细胞绝对值、34例(77.27%)T淋巴细胞计数、38例(86.36%)CD4^+T、32例(72.73%)CD8^+T下降,28例(63.64%)中性粒细胞百分比、38例(86.36%)IL-6、30例(68.18%)IL-10、38例(86.36%)C反应蛋白、42例(95.45%)血清淀粉样蛋白A升高。入院时胸部CT示多为单发或多发磨玻璃影,部分患者可见少许实变,病灶主要沿支气管血管束及胸膜下分布。随着病情发展,病变范围可迅速增大,实变与磨玻璃影共见,出院时复查磨玻璃影部分吸收,实变范围缩小,密度减低,部分可见间质性改变。结论COVID-19患者以呼吸道症状为主,辅助检查可见淋巴细胞减少及典型的胸部CT影像特征,影像学吸收明显滞后。
Objective To summarize the clinical characteristics of COVID-19 patients who were cured and discharged from hospital,and to improve treatment level.Methods The clinical symptoms,laboratory examination,imaging features,treatment and prognosis of 44 patients with COVID-19 were analyzed.Results The main symptoms of patients with COVID-19 were fever,fatigue,cough,expectoration,chest distress and shortness of breathing,panting,poor appetite,etc.And the symptoms such as cough,chest distress and shortness of breath after activity,and fatigue recovered slowly.Among COVID-19 patients on admission,10(22.73%)leucocyte count,24(54.55%)absolute lymphocytes,34(77.27%)T lymphocyte count,38(86.36%)CD4^+T,32(72.73%)CD8^+T decreased,while 28(63.64%)percentage of neutrophils,38(86.36%)IL-6,30(68.18%)IL-10,38(86.36%)CRP,42(95.45%)SAA increased.And on admission,chest CT showed mostly single or multiple ground-glass opacity(GGO),a little consolidation in some patients,and the lesions were mainly distributed along the bronchovascular bundle and subpleural.As the disease progressed,the range of lesions rapidly increased,consolidation and GGO could be seen together.At the time of discharge,chest CT showed GGO partially absorbed,consolidation range reduced,density reduced,but interstitial lesions in some patients.Conclusion COVID-19 patients mainly have respiratory symptoms.The auxiliary examination shows reduced lymphocyte and typical chest CT image features,and the imaging absorption is significantly delayed.
作者
邹义龙
范存愈
徐波
刘尧蓓
王波
张继先
余贻汉
Zou Yilong;Fan Cunyu;Xu Bo;Liu Yaobei;Wang Bo;Zhang Jixian;Yu Yihan(Hubei Provincial Hospital of Integrated Traditional Chinese & Western Medicine, Wuhan 430000, China;Maternal and Child Health Hospital of Hubei, Wuhan 430000, China;Center for Postdoctoral Studies, Liaoning University of Traditional Chinese Medicine, Shenyang 110034, China)
出处
《成都医学院学报》
CAS
2020年第4期499-502,共4页
Journal of Chengdu Medical College
