期刊文献+

雷珠单抗联合激光治疗增殖型糖尿病视网膜病变的临床疗效分析 被引量:3

Clinical effect of leizhumab combined with laser in the treatment of proliferative diabetic retinopathy
暂未订购
导出
摘要 目的分析增殖型糖尿病视网膜病变采用雷珠单抗联合激光治疗的临床疗效。方法选取我院2018年8月~2019年10月收治的100例(142眼)增殖型糖尿病视网膜病变患者为研究对象,随机分为两组,对照组患者单独采用激光治疗,观察组在对照组基础上联合雷珠单抗治疗,对比两组治疗前后最佳矫正视力(BCVA)、黄斑中心凹厚度(CMT)、眼压变化情况。结果与对照组对比,观察组治疗1个月后、治疗3个月后以及治疗6个月后的BCVA、CMT、眼压均更低(P<0.05)。结论增殖型糖尿病视网膜病变采用雷珠单抗联合激光治疗的临床疗效显著,利于改善患者的BCVA、CMT与眼压,值得推广。 Objective To analyze the clinical effect of the treatment of proliferative diabetic retinopathy with leizhumab and laser.Methods A total of 100 patients(142 eyes)with proliferative diabetic retinopathy admitted to our hospital from August 2018 to October 2019 were randomly divided into two groups.The patients in the control group were treated with laser alone.The observation group was treated with leizhumab on the basis of the control group.The changes of BCVA,CMT and IOP were compared before and after treatment Situation.Results Compared with the control group,the BCVA,CMT and IOP of the observation group were lower after 1 month,3 months and 6 months(P<0.05).Conclusion The clinical effect of the treatment of proliferative diabetic retinopathy with leizhumab combined with laser is significant,which is beneficial to the improvement of BCVA,CMT and intraocular pressure,and it is worth popularizing.
作者 梁静 Liang Jing(Ophthalmology,Shenzhen Hospital,Southern Medical University,Shenzhen,Guangdong Province)
出处 《首都食品与医药》 2020年第14期42-43,共2页 Capital Food Medicine
关键词 增殖型 糖尿病视网膜病变 雷珠单抗 激光 联合治疗 临床疗效 proliferative type diabetic retinopathy leizhumab laser combined therapy clinical effect
  • 相关文献

参考文献8

二级参考文献76

  • 1Ga Eun Cho,Hee Yun Cho,Yun Taek Kim.Change in subfoveal choroidal thickness after argon laser panretinal photocoagulation[J].International Journal of Ophthalmology(English edition),2013,6(4):505-509. 被引量:15
  • 2罗清礼,王琳,吴海英.激光光凝后视网膜色素上皮、Bruch膜和脉络膜超微结构改变[J].中华眼科杂志,2004,40(10):692-695. 被引量:13
  • 3颜华,许瀛海.增生型糖尿病视网膜病变玻璃体切割手术后再出血病因及治疗[J].中华眼底病杂志,2007,23(4):238-240. 被引量:25
  • 4Oshima Y,Shima C,Wakabayashi T,et al.Microincision vitrectomy surgery and intravitreal bevacizumab as a surgical adjunct to treat diabetic traction retinal detachment[J]. Ophthalmology,2009,116(5):927-938.DOI:10.1016/j. ophtha.2008.11.005.
  • 5Yeoh J,Williams C,Allen P,et al.Avastin as an adjunct to vitrectomy in the management of severe proliferative diabetic retinopathy:a prospective case series[J].Clin Experiment Ophthalmol,2008,36(5):449-454.
  • 6Holladay JT.Proper method for caculating average visual acuity [J].J Refract Surg,1997,13(4):388-391.
  • 7Pece A,Isola V,Piermarocchi S,et al.Efficacy and safty of anti-vascular endothelial growth factor(VEGF)therapy with intravitreal ranibizumab(Lucentis)for naive retinal vein occlusion:1-year follow-up[J].Br J Ophthalmol,2011,95(1):56-68.DOI:10.1136/bjo.2009.174060.
  • 8Abegg M,Tappeiner C,Wolf-Schnurrbusch U,et al. Treatment of branch retinal vein occlusion induced macular edema with bavacizumab[J],BMC Ophthalmol,2008,8(9):18.DOI:10.1186/1471-2415-8-18.
  • 9Pacella Ef Pacella F,La torre G,et al.Testing the effectiveness of intravitreal Ranibizumab during 12 months of follow-up in venous occlusion treatment[J].Clin Ter,2012,163(6):413-422.
  • 10Campochiaro PA,Sophie R,Pearlman J,et al.Long-term outcomes in patients with retinal vein occlusion treated with ranibizumab:the RETAIN study[J].Ophthalmology,2014, 121(1):209-219.DOI:10.1016/j.ophtha.2013.08.038.

共引文献169

同被引文献37

引证文献3

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部