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右美托咪定对剖宫产产妇镇痛、并发症及S100β蛋白的影响 被引量:6

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摘要 目的研究右美托咪定对剖宫产产妇镇痛、并发症、S100β蛋白的影响。方法选取行剖宫产的产妇70例,按照随机数字表法分为对照组和右美托咪定组,各35例。对照组患者给予舒芬太尼,右美托咪定组患者给予盐酸右美托咪定麻醉。采用布氏舒适评分(BCS)、Ramsay评分评估患者疼痛情况,检测患者S100β蛋白水平以及血流动力学相关指标[主要记录进入手术室时(T0)、手术结束时(T1)、拔管结束时(T2)、出手术室时(T3)的心率(HR)、收缩压(SBP)、舒张压(DBP)及血氧饱和度(SpO2)水平],统计患者并发症发生率。结果在T1、T2和T3时,右美托咪定组BCS评分、Ramsay评分优于对照组,差异有统计学意义(P<0.05)。在T1、T2和T3时,右美托咪定组S100β蛋白低于对照组,差异有统计学意义(P<0.05)。在T2和T3时,右美托咪定组HR、SBP、DBP及SpO2水平低于对照组,差异有统计学意义(P<0.05)。右美托咪定组患者并发症发生率为5.71%,低于对照组并发症发生率22.86%,差异有统计学意义(P<0.05)。结论右美托咪定对剖宫产产妇镇痛效果显著,能够有效改善患者S100β蛋白水平,降低其并发症发生。
出处 《广东医学》 CAS 2020年第12期1272-1275,共4页 Guangdong Medical Journal
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