摘要
女性生殖道微生物群(female reproductive tract microbiota)指定殖在女性生殖道中的微生物的集合,其动态变化、功能和与人体生理功能关系的研究不断取得进展。近年,借助第二代高通量测序和宏基因组测序等新研究手段,不断有研究表明女性生殖道微生物可能在生育过程中起到重要作用,异常生殖道菌群可能导致不孕,还与流产、胎膜早破、早产等不良孕产相关。本文对近年生殖道菌群对女性生育力的影响的研究进展进行综述,以期给今后此类研究的方向提供思路。
Female reproductive tract microbiota refers to the collection of microorganisms in female reproductive tract,its dynamics,function and interactions with host have been investigated in depth.In recent years,the advancement of next-generation sequencing and metagenomic sequencing and other technologies has transformed researches on reproductive tract microbial community,unveiling its possible impact on reproduction function.Furthermore,abnormal reproductive tract microbiota may predispose to infertility,miscarriage,premature rupture of membranes,premature delivery and other diseases.Here we review the current literature that focuses on female reproductive tract microbiota and highlight its possible role on female fertility.
作者
樊梓怡
刘芬婷
李蓉
Fan Ziyi;Liu Fenting;Li Rong(Reproductive Medical Center,Department of Obstetrics and Gynecology,Peking University Third Hospital,Beijing 100191,China)
出处
《中华生殖与避孕杂志》
CAS
CSCD
北大核心
2020年第6期515-520,共6页
Chinese Journal of Reproduction and Contraception
关键词
生殖道微生物群
生育力
分子微生物生态学
Female reproductive tract microbiota
Fertility
Molecular microbial ecology
