摘要
目的探讨术前不留置胃管对腹腔镜结直肠癌根治术患者免疫球蛋白M(IgM)和IgG水平的影响。方法选取2015年1月至2020年1月间渭南市中心医院收治的60例结直肠癌患者,采用随机数表法分为观察组和对照组,每组30例。对照组患者于术前常规留置胃管,造瘘口或肛门排气后拔除,观察组患者不留置胃管,比较两组患者术后恢复情况、IgM和IgG水平及并发症发生情况。结果观察组患者首次肠鸣音时间、首次排气时间、首次排便时间、首次下床时间及住院时间均短于对照组,差异均有统计学意义(均P<0.05)。术前,两组患者IgM和IgG水平比较,差异无统计学意义(P>0.05)。术后,两组患者IgM和IgG水平均降低,但观察组高于对照组,差异均有统计学意义(均P<0.05)。两组患者切口感染、吻合口漏和恶心呕吐发生率比较,差异无统计学意义(P>0.05)。观察组患者咽痛和腹胀腹泻发生率均低于对照组,差异均有统计学意义(均P<0.05)。结论术前不留置胃管有利于腹腔镜结直肠癌根治术患者术后恢复,降低并发症发生率,对免疫功能影响较小,值得临床借鉴。
Objective To investigate the effect of preoperative non indwelling gastric catheter on levels of immunoglobulin,say,immunoglobulin M(IgM)and IgG in patients undergoing laparoscopic radical resection for colorectal cancer.Methods A total of 60 patients with colorectal cancer who admitted to Weinan Central Hospital from January 2015 to January 2020 were selected as the research subjects and they were randomly divided into an observation group and a control group with 30 patients in each group.In the control group,indwelling gastric catheter was performed before surgery,and was removed after orifice fistula or anal exhaust.In the observation group,gastric catheter was not indwelled.Postoperative recovery,IgM and IgG levels and complications were compared between the two groups.Results Time of return of bowel sounds,time to first postoperative exhaustion and defecation,time to out-of-bed activity and the length of hospital stay were significantly shorter in the observation group than in the control group(all P<0.05).There was no statistically significant difference in IgM and IgG levels between the two groups before surgery(P>0.05).The above indicators were significantly reduced in both groups after surgery,and the observation group was significantly higher than the control group(all P<0.05).There was no statistically significant difference in the incidence of incision infection,anastomotic leakage and malignant vomiting between the two groups(P>0.05).The incidence of pharyngeal pain and abdominal distension and diarrhea was significantly lower in the observation group than in the control group(all P<0.05).Conclusion Non indwelling gastric catheter before surgery is conducive to the postoperative recovery in patients undergoing laparoscopic radical resection for colorectal cancer.It reduce the incidence of complications and have little impact on the immune function and is worthy of clinical reference.
作者
赵渭东
王雅辉
ZHAO Wei-dong;WANG Ya-hui(Department of Oncological Surgery,Weinan Central Hospital,Weinan 714000,China)
出处
《中国肿瘤临床与康复》
2020年第5期561-563,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
结直肠肿瘤
留置胃管
腹腔镜结直肠癌根治术
免疫球蛋白M
免疫球蛋白G
Colorectal tumors
indwelling Gastric tube
Laparoscopic radical operation for colorectal cancer
Immunoglobulin M
Immunoglobulin G
