摘要
目的探讨结核性与非特异性缩窄性心包炎的临床特征,为临床诊断提供参考。方法回顾性分析2012年11月-2019年5月诊断为缩窄性心包炎患者的临床资料,依据心包病理检查结果,分为结核性缩窄性心包炎组(42例)与非特异性缩窄性心包炎组(11例)。结果两组比较,男性、年龄大、病程短、发热史、结核中毒症状、合并肺/其他部位结核活动、结核菌素纯蛋白衍生物(PPD)皮试阳性、结核分枝杆菌抗体IgG阳性、结核感染T细胞检测阳性、心包积液腺苷脱氨酶>40 U/L,这10项临床特征在结核性缩窄性心包炎中更常见,差异有统计学意义(P<0.05)。结论结核性缩窄性心包炎患者在性别、发病年龄、临床表现、实验室检查等方面有着自身特点,这些临床特征能为鉴别结核性与非特异性缩窄性心包炎提供一定的诊断价值。
Objective To investigate the clinical characteristics of tuberculosis and nonspecific constrictive pericarditis to provide data for better clinical diagnosis.Methods The medical records of 53 patients with constrictive pericarditis diagnosed from November 2012 to May 2019 were reviewed,including tuberculous cases (n=42) and nonspecific cases (n=11) according to pericardial pathology.Results Tuberculous constrictive pericarditis was significantly associated with males,old people,short duration of disease,fever,tuberculosis symptoms,active tuberculosis in other sites,higher percentage of purified protein derivation (PPD) positive skin test,higher prevalence of tuberculosis IgG antibody,higher rate of positive T-cell enzyme-linked immunosorbent spot assay,and positive adenosine deaminase (ADA) in pericardial effusion than nonspecific constrictive pericarditis (P<0.05).Conclusions Tuberculous constrictive pericarditis has characteristic features in sex,age of onset,clinical manifestation,laboratory test,which valuable for clinical diagnosis.
作者
李彪
陈范才
贺丹
曹理言
严新光
曾唐怡
谢和宾
LI Biao;CHEN Fancai;HE Dan;CAO Liyan;YAN Xinguang;ZENG Tangyi;XIE Hebin(Department of Nosocomial Infection Management,Changsha Central Hospital of South China University,Changsha 410007,China)
出处
《中国感染与化疗杂志》
CAS
CSCD
北大核心
2020年第4期384-387,共4页
Chinese Journal of Infection and Chemotherapy
关键词
缩窄性心包炎
结核病
结核感染T细胞检测
constrictive pericarditis
tuberculosis
T-cell enzyme-linked immunosorbent spot assay
